88928-69-2

Basic information

• Product Name: methyl 1-benzyl-1,2,5,6-tetrahydropyridine-3-carboxylate
• CAS NO: 88928-69-2
• Molecular Weight: 231.294
• Mol File: 88928-69-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 1-benzyl-1,2,5,6-tetrahydropyridine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1-benzyl-1,2,5,6-tetrahydropyridine-3-carboxylate(88928-69-2)
• EPA Substance Registry System: methyl 1-benzyl-1,2,5,6-tetrahydropyridine-3-carboxylate(88928-69-2)

Safety Data

• Hazardous Substances Data: 88928-69-2(Hazardous Substances Data)

Usage

General Description

Methyl 1-benzyl-1,2,5,6-tetrahydropyridine-3-carboxylate is a chemical compound with the molecular formula C16H19NO2. It is commonly used in the synthesis of pharmaceuticals and as an intermediate in organic chemical reactions. methyl 1-benzyl-1,2,5,6-tetrahydropyridine-3-carboxylate is a carboxylate ester, which means it contains a carbonyl group connected to an oxoacid by an ester group. It can be used as a building block in the synthesis of various pharmaceutical compounds and is also used in research and development of new drugs. Methyl 1-benzyl-1,2,5,6-tetrahydropyridine-3-carboxylate is commonly found in chemical labs and is not intended for direct consumer use.

Upstream product

• 6197-39-3 1,2,5,6-tetrahydro-3-pyridinecarboxylic acid methyl ester hydrochloride 
• 100-39-0 benzyl bromide 
• 63-75-2 arecoline 
• 300-08-3 arecoline hydrobromide 
• 793-19-1 bis(2-methoxycarbonylethyl)benzylamine 
• 57611-47-9 1-benzyl-4-oxo-piperidine-3-carboxylic acid methyl ester 
• 955998-64-8 methyl 1-benzyl-4-hydroxypiperidine-3-carboxylate 
• 93-60-7 methyl 3-pyridinecarboxylate 
• 6516-41-2 1-benzyl-3-(methoxycarbonyl)pyridinium bromide 
• 100-46-9 benzylamine 

Downstream Products

• 857051-22-0 methyl 1-benzyl-3-butyl-1,2,3,6-tetrahydropyridine-3-carboxylate 
• 1452108-88-1 sodium 1-benzyl-1,2,5,6-tetrahydropyridine-3-carboxylate 
• 857051-27-5 N-((1-benzyl-3-butyl-1,2,3,6-tetrahydropyridin-3-yl)methyl)-N-butyl-2,2,2-trifluoroacetamide 
• 857051-36-6 N-[(1-benzyl-3-butyl-1,2,3,6-tetrahydropyridin-3-yl)methyl]-2,2,2-trifluoroacetamide 
• 857051-42-4 (1-benzyl-3-butyl-1,2,3,6-tetrahydro-pyridin-3-ylmethyl)-butyl-amine 
• 857051-26-4 (1-benzyl-3-butyl-1,2,3,6-tetrahydropyridin-3-yl)methylamine 
• 857051-23-1 1-benzyl-3-butyl-1,2,3,6-tetrahydropyridine-3-carbaldehyde 
• 252056-58-9 dimethyl 4-(4-fluorophenyl)-1,4,5,6-tetrahydropyridine-1,3-dicarboxylate 
• 955998-65-9 methyl 4-(4-fluorophenyl)-1,4,5,6-tetrahydropyridine-3-carboxylate 

Relevant articles and documents

N-Heteroarylmethyl-5-hydroxy-1,2,5,6-tetrahydropyridine-3-carboxylic acid a novel scaffold for the design of uncompetitive α-glucosidase inhibitors

Abstract The enzyme α-glucosidase has attracted interest owing to its involvement in the digestive process of carbohydrate, its role in intracellular glycoprotein trafficking, tumorigenesis and viral infection. In this study, several members of a new family of N-heteroarylmethyl substituted azasugars were synthesized and evaluated as α-glucosidase inhibitors. We systematically investigated the effect of different N-substituents as well as the role of hydroxyl and carboxylate moieties on the piperidine ring. The compounds N-heteroarylmethyl-5-hydroxy-1,2,5,6-tetrahydropyridine-3-carboxylic acid emerged as potent α-glucosidase inhibitors. Unlike Acarbose and other clinically relevant α-glucosidase inhibitors, these compounds act through a reversible uncompetitive mechanism of inhibition which make them attractive candidates for drug development.

An approach to the tricyclic core of madangamines based upon a biogenetic scheme

(Chemical Equation Presented) A short synthesis of intermediates possessing the tricyclic core of natural madangamines, bioactive alkaloids found in marine sponges, is described. The key reaction entails the condensation of the sodium salt of diethylaceto