89-74-7 Usage
Description
2',4'-Dimethylacetophenone is an organic compound with a molecular formula of C9H12O. It is characterized by a sweet, floral, woody, and minty odor. 2',4'-Dimethylacetophenone is known for its naphthyl phenolic, coumarin, coconut, oily, and chemical taste characteristics at a concentration of 5 ppm. It has been reported to occur naturally in various sources such as cinnamon bark, wine, tea, watercress, and dried bonito.
Uses
Used in Flavor and Fragrance Industry:
2',4'-Dimethylacetophenone is used as a flavoring agent for its sweet chemical, slightly fruity cherry, and powdery coumarin-like aroma characteristics. It is also used as a fragrance ingredient due to its slightly camphoraceous scent with a hint of coconut.
Used in Food Industry:
In the food industry, 2',4'-Dimethylacetophenone is used as a flavor enhancer to impart a unique taste and aroma to various food products. Its sweet and woody notes can add depth and complexity to the flavor profile of dishes.
Used in Beverage Industry:
2',4'-Dimethylacetophenone is utilized in the beverage industry to add a distinct flavor and aroma to alcoholic and non-alcoholic drinks. Its sweet and slightly fruity notes can enhance the taste of beverages, making them more appealing to consumers.
Used in Cosmetics and Personal Care Industry:
In the cosmetics and personal care industry, 2',4'-Dimethylacetophenone is used as a fragrance ingredient in various products such as perfumes, colognes, soaps, and lotions. Its pleasant and versatile scent makes it a popular choice for creating appealing scents in personal care products.
Used in Pharmaceutical Industry:
2',4'-Dimethylacetophenone can be used in the pharmaceutical industry as a starting material for the synthesis of various drugs and medicinal compounds. Its unique chemical properties make it a valuable component in the development of new medications.
Overall, 2',4'-Dimethylacetophenone is a versatile compound with a wide range of applications across different industries, primarily due to its distinct and appealing scent and taste characteristics.
Preparation
By condensation of acetylchloride and m-xylene in the presence of aluminum chloride or in the presence of ferric
chloride
Synthesis Reference(s)
The Journal of Organic Chemistry, 46, p. 2974, 1981 DOI: 10.1021/jo00327a028
Check Digit Verification of cas no
The CAS Registry Mumber 89-74-7 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 9 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 89-74:
(4*8)+(3*9)+(2*7)+(1*4)=77
77 % 10 = 7
So 89-74-7 is a valid CAS Registry Number.
89-74-7Relevant articles and documents
Pyrazoles: 'one-pot' synthesis from arenes and carboxylic acids
Gong, Ming,Kim, Jung Keun,Kovalev, Vladimir V.,Kovaleva, Olga V.,Shokova, Elvira A.,Tafeenko, Viktor A.,Wu, Yangjie
supporting information, p. 5625 - 5638 (2020/08/21)
A rapid and efficient method for 'one-pot' synthesis of pyrazoles from (hetero)arenes and carboxylic acids via successive formation of ketones and β-diketones followed by heterocyclization with hydrazine has been developed. The utility of the RCOOH/TfOH/TFAA acylation system for intermediate production of ketones and 1,3-diketones is a key feature of this approach. The preliminary evaluation of the anticancer activity of the synthesized pyrazoles is performed.
Isopropanol as a hydrogen source for single atom cobalt-catalyzed Wacker-type oxidation
An, Yue,Chen, Bo,Gao, Shuang,Huang, Guanwang,Luo, Huihui,Shang, Sensen,Wang, Lianyue
, p. 2769 - 2773 (2020/06/17)
The first example of a heterogeneous cobalt catalytic system for Wacker-type oxidation catalyzed by a single atom dispersed Co-N/C catalyst using alcohol as the hydrogen source under an oxygen atmosphere is presented. By combining a well-designed, controlled experiment and various methods of characterization, we determined that single atom cobalt was the active center rather than nanoparticle or oxide counterparts.
Efficient Palladium(0) supported on reduced graphene oxide for selective oxidation of olefins using graphene oxide as a ‘solid weak acid’
Gao, Xi,Zhou, Jianhao,Peng, Xinhua
, p. 73 - 78 (2019/02/06)
Selective oxidation of olefin derivatives to ketones has made innovative development over palladium(0) supported on reduced graphene oxide. Compared to traditional Wacker oxidation, the novel method offers an economical and environment-friendly option by using graphene oxide (GO) as a ‘solid weak acid’ instead of classical homogeneous catalysts like H2SO4 and CF3COOH. X-ray diffraction, X-ray photoelectron spectroscopy, scanning electron microscope and transmission electron microscopy images of Pd0/RGO showed that the nanoscaled Pd particles generated at the flake structure of reduced graphene oxide. Under optimized condition, up to 44 kinds of ketones with different structures can be prepared with excellent yields.