89007-61-4

Basic information

• Product Name: Cyclopropanecarboxylic acid, 2,2-dimethyl-, ethyl ester, (S)-
• CAS NO: 89007-61-4
• Molecular Formula: C8H14O2
• Molecular Weight: 142.198
• Mol File: 89007-61-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Cyclopropanecarboxylic acid, 2,2-dimethyl-, ethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxylic acid, 2,2-dimethyl-, ethyl ester, (S)-(89007-61-4)
• EPA Substance Registry System: Cyclopropanecarboxylic acid, 2,2-dimethyl-, ethyl ester, (S)-(89007-61-4)

Safety Data

• Hazardous Substances Data: 89007-61-4(Hazardous Substances Data)

Usage

General Description

"Cyclopropanecarboxylic acid, 2,2-dimethyl-, ethyl ester, (S)-" is a chemical compound used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is an ester, meaning it is derived from an organic acid and an alcohol, and it has a cyclopropane ring in its structure. The (S)- designation indicates that it is the enantiomer of the compound, which means it has a specific arrangement of atoms that gives it a certain chirality. Cyclopropanecarboxylic acid, 2,2-dimethyl-, ethyl ester, (S)- may have potential applications in the development of new drugs and agricultural products due to its unique structure and properties.

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 115-11-7 isobutene 

Downstream Products

• 75885-58-4 (S)-2,2-dimethylcyclopropanecarboxamide 

Relevant articles and documents

A reusable, insoluble polymer-bound bis(oxazoline) (IPB-box) for highly enantioselective heterogeneous cyclopropanation reactions

A reusable, insoluble polystyrene-supported bis(oxazoline) was developed, affording e.e.s > 90% in the heterogeneous enantioselective cyclopropanation of styrene and 1,1-disubstituted alkenes with ethyl diazoacetate.

Siliceous mesocellular foam-supported aza(bisoxazoline)-copper catalysts

Aza(bisoxazoline) was easily immobilized on siliceous mesocellular foam (MCF) in a systematic approach. It was found that silanol precapping, linker group flexibility, ligand loading, and silanol postcapping were important factors to consider in optimizing silica-supported aza(bisoxazoline) catalysts. The optimized MCF-supported aza(bisoxazoline)-copper catalyst offered the same enantioselectivity as its homogeneous counterpart, and excellent recyclability. The heterogenized catalyst showed a much higher chemoselectivity in a short reaction time. The heterogenized aza(bisoxazoline)-copper(I) catalyst was successfully applied to a circulating flow-type packed bed reactor with excellent productivity and enantioselectivity. The circulating flow-type reactor was found to be very useful for gas-generating catalytic reactions such as cyclopropanation reaction.

Bis(oxazolines) as Chiral Ligands in Metal-Catalyzed Asymmetric Reactions. Catalytic, Asymmetric Cyclopropanation of Olefins

-