89181-64-6 Usage
General Description
2,5-Piperazinedione, 3-(hydroxymethyl)- (6CI,7CI,9CI) is a chemical compound with the molecular formula C5H8N2O3. It is a piperazine derivative and contains a hydroxymethyl group. 2,5-Piperazinedione, 3-(hydroxymethyl)- (6CI,7CI,9CI) is commonly used in the pharmaceutical industry and is known for its potential biological activities, such as antitumor and antibacterial properties. It is also used in the synthesis of various pharmaceutical products and can act as a building block for the creation of new drugs. Additionally, 2,5-Piperazinedione, 3-(hydroxymethyl)- (6CI,7CI,9CI) has been studied for its potential role in drug delivery and targeting specific receptors in the body.
Check Digit Verification of cas no
The CAS Registry Mumber 89181-64-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,1,8 and 1 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 89181-64:
(7*8)+(6*9)+(5*1)+(4*8)+(3*1)+(2*6)+(1*4)=166
166 % 10 = 6
So 89181-64-6 is a valid CAS Registry Number.
89181-64-6Relevant articles and documents
The Ugly Duckling Metamorphosis: The Ammonia/Formaldehyde Couple Made Possible in Ugi Reactions.
Rosalba, Thaissa Pasquali F.,Kas, Samia Sayegh A.,Sampaio, Ana Beatriz S.,Salvador, Carlos Eduardo M.,Andrade, Carlos Kleber Z.
, p. 2831 - 2842 (2021/05/13)
Ugi reactions are still a challenge when the concomitant use of ammonia and formaldehyde is required. Herein, we propose a strategy to overcome this challenge using hexamethylenetetramine (HMTA) as a singular key for the employment of these two simple starting materials in the Ugi reaction. Acylaminoacetamide derivatives were prepared in good to excellent yields by this new methodology. The scope and optimization of the reaction conditions were investigated. This novel methodology was successfully applied in the synthesis of two different diketopiperazines (DKPs) using the Ugi/Deprotection+Activation/Cyclization (UDAC) method. A continuous flow approach was also used in this methodology.
