89241-42-9Relevant articles and documents
Lewis acid mediated one-pot synthesis of aryl/heteroaryl-fused carbazoles involving a cascade Friedel-Crafts alkylation/electrocyclization/aromatization reaction sequence
Sureshbabu, Radhakrishnan,Saravanan, Velu,Dhayalan, Vasudevan,Mohanakrishnan, Arasambattu K.
, p. 922 - 935 (2011/04/22)
A Lewis-acid-mediated domino reaction of 2/3-(bromomethyl)indoles with arenes/heteroarenes led to the formation of the corresponding annulated carbazoles. This three-step one-pot transformation proceeds by sequential Lewis acid catalysed Friedel-Crafts alkylation, electrocyclization and aromatization reactions. The strategy is highly efficient for the assembly of complex aryl/heteroaryl-fused carbazoles.
A one pot synthesis of annulated carbazole analogs
Mohanakrishnan, Arasambattu K.,Dhayalan, Vasudevan,Arul Clement,Sureshbabu, Ramalingam Balamurugan Radhakrishnan,Senthil Kumar, Natarajan
scheme or table, p. 5850 - 5854 (2009/04/06)
A ZnBr2-mediated arylation of N-protected 2/3-bromomethylindoles containing an electron-deficient malonylidene unit with arenes at 80 °C led to the formation of arylated products, which on unprecedented 1,5-sigmatropic rearrangement followed by electrocyclization and subsequent aromatization with loss of diethylmalonate furnished the corresponding annulated carbazoles in reasonable yields.
