89434-04-8 Usage
General Description
4-Fluoroindole-3-acetonitrile is a chemical compound with the molecular formula C10H7FN2. It is a fluoro-substituted derivative of indole-3-acetonitrile, which is used as a versatile synthetic building block in organic chemistry. 4-FLUOROINDOLE-3-ACETONITRILE has a wide range of applications in the pharmaceutical industry, particularly in the synthesis of biologically active molecules and pharmaceutical intermediates. It is also used in the production of agrochemicals and other fine chemicals. 4-Fluoroindole-3-acetonitrile is known for its high reactivity and ability to undergo various chemical transformations, making it a valuable compound for organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 89434-04-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,4,3 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 89434-04:
(7*8)+(6*9)+(5*4)+(4*3)+(3*4)+(2*0)+(1*4)=158
158 % 10 = 8
So 89434-04-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H7FN2/c11-8-2-1-3-9-10(8)7(4-5-12)6-13-9/h1-3,6,13H,4H2
89434-04-8Relevant articles and documents
Asymmetric Dearomatizing Fluoroamidation of Indole Derivatives with Dianionic Phase-Transfer Catalyst
Egami, Hiromichi,Hotta, Ryo,Otsubo, Minami,Rouno, Taiki,Niwa, Tomoki,Yamashita, Kenji,Hamashima, Yoshitaka
supporting information, p. 5656 - 5660 (2020/07/14)
Asymmetric dearomatizing fluorocyclization of indole derivatives was investigated using a dicarboxylate phase-transfer catalyst. This reaction proceeds under mild reaction conditions to provide fluoropyrroloindoline derivatives in a highly enantioselective manner. Various substitution patterns on the indole ring are well tolerated. To facilitate the reaction and ensure reproducibility, the addition of water is essential, and its possible role is discussed.
