894808-41-4

Basic information

• Product Name: 5-Bromo-N,N-dimethyl-3-(4-methyl-1,4-diazepan-1-yl)pyrazin-2-amine
• Synonyms: 5-Bromo-N,N-dimethyl-3-(4-methyl-1,4-diazepan-1-yl)pyrazin-2-amine
• CAS NO: 894808-41-4
• Molecular Weight: 314.228
• Mol File: 894808-41-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Bromo-N,N-dimethyl-3-(4-methyl-1,4-diazepan-1-yl)pyrazin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-N,N-dimethyl-3-(4-methyl-1,4-diazepan-1-yl)pyrazin-2-amine(894808-41-4)
• EPA Substance Registry System: 5-Bromo-N,N-dimethyl-3-(4-methyl-1,4-diazepan-1-yl)pyrazin-2-amine(894808-41-4)

Safety Data

• Hazardous Substances Data: 894808-41-4(Hazardous Substances Data)

Upstream product

• 4318-37-0 1-Methylhomopiperazine 
• 84539-07-1 2-(N,N-dimethyl)amino-3,5-dibromopyrazine 

Relevant articles and documents

2,3-Diaminopyrazines as rho kinase inhibitors

Inhibition of rho kinase (ROCK) has been recognized as an important target for a number of diseases, including glaucoma. Herein we report SAR development around two hits from a kinase library that led to the discovery of the ROCK inhibitor compound 38. In vitro and in vivo analysis of this compound, including its effects in a monkey model of glaucoma will be discussed.