89615-42-9Relevant articles and documents
Anti-norovirus activity of C7-modified 4-amino-pyrrolo[2,1-f][1,2,4]triazine C-nucleosides
Groaz, Elisabetta,Herdewijn, Piet,Li, Qingfeng,Neyts, Johan,Rocha-Pereira, Joana
, (2020/04/15)
Synthetic nucleoside analogues characterized by a C–C anomeric linkage form a family of promising therapeutics against infectious and malignant diseases. Herein, C-nucleosides comprising structural variations at the sugar and nucleobase moieties were exam
Chemical Synthesis of Ketopentose-5-phosphates
Wei, Wei-Chih,Chang, Che-Chien
, p. 3033 - 3040 (2017/06/20)
A chemical synthesis of ketopentose-5-phosphates that are involved in the pentose phosphate pathway has been developed. The ketopentose phosphates, d-ribulose-5-phosphate and d-xylulose-5-phosphate, were prepared in five steps starting from known intermed
Synthesis and evaluation of: N -alkylated analogues of aza-galacto-fagomine-potential pharmacological chaperones for Krabbe disease
Viuff, Agnete H.,Jensen, Henrik H.
, p. 8545 - 8556 (2016/09/28)
Seven novel alkylated or acylated analogues of hexahydropyridazine aza-galacto-fagomine (AGF) was prepared and studied as glycosidase inhibitors with the aim of increasing inhibitory potency and selectivity. The enzyme galactocerebrosidase, implicated in Krabbe disease, was found to be potently inhibited by n-butyl N2-alkylated AGF.