896466-75-4

Basic information

• Product Name: AT 9283, dihydrate
• Synonyms: AT 9283, dihydrate;NGMUUTYKXSUSDB-UHFFFAOYSA-N
• CAS NO: 896466-75-4
• Molecular Formula: C19H25N7O3
• Mol File: 896466-75-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: AT 9283, dihydrate(CAS DataBase Reference)
• NIST Chemistry Reference: AT 9283, dihydrate(896466-75-4)
• EPA Substance Registry System: AT 9283, dihydrate(896466-75-4)

Safety Data

• Hazardous Substances Data: 896466-75-4(Hazardous Substances Data)

Usage

Description

AT 9283, dihydrate is a chemical compound belonging to the class of pyrazole inhibitors. It is a potent and selective inhibitor of cyclin-dependent kinases CDK4 and CDK6, which are crucial in cell cycle progression and often overexpressed in various cancer types. AT 9283, dihydrate has shown promising antiproliferative activity in preclinical studies and holds potential for treating various solid tumors and hematological malignancies. Additionally, it has demonstrated synergy with other anticancer agents, positioning it as a promising candidate for combination therapy. Its therapeutic potential is currently being evaluated in clinical trials for cancer treatment.

Uses

Used in Pharmaceutical Industry:
AT 9283, dihydrate is used as an anticancer agent for its ability to inhibit the activity of CDK4 and CDK6, proteins that are often overexpressed in various cancer types. This inhibition helps in controlling cell cycle progression, thereby exhibiting antiproliferative activity against cancer cells.
Used in Cancer Treatment:
AT 9283, dihydrate is used as a therapeutic agent for the treatment of various solid tumors and hematological malignancies due to its demonstrated antiproliferative effects in preclinical studies.
Used in Combination Therapy:
AT 9283, dihydrate is used in combination with other anticancer agents to enhance the overall therapeutic effect and overcome resistance to conventional treatments, as it has shown synergy with other drugs in preclinical studies.
Used in Clinical Trials:
AT 9283, dihydrate is utilized in clinical trials to further evaluate its therapeutic potential and safety for the treatment of cancer, with the aim of advancing its development as a novel treatment option.