896466-76-5

Basic information

• Product Name: AT9283
• Synonyms: AT9283;AT 9283, (2S)-2-hydroxy-propanoic acid salt;(2S)-2-Hydroxypropanoic acid compd. with N-cyclopropyl-N'-[3-[6-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]urea;T9283;1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea (S)-2-;RWYNKTMXFIMBFE-WNQIDUERSA-N
• CAS NO: 896466-76-5
• Molecular Formula: C19H23N7O2.C3H6O3
• Molecular Weight: 381.4316
• EINECS: 604-604-1
• Mol File: 896466-76-5.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.45g/cm³
• Refractive Index: 1.714
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: AT9283(CAS DataBase Reference)
• NIST Chemistry Reference: AT9283(896466-76-5)
• EPA Substance Registry System: AT9283(896466-76-5)

Safety Data

• Hazardous Substances Data: 896466-76-5(Hazardous Substances Data)

Usage

Description

AT9283 is a potent AuroraA/AuroraB and multi-kinase inhibitor, which has demonstrated the ability to inhibit the growth and survival of multiple solid tumor cell lines. It has also shown efficacy in mouse xenograft models and is a COVID-19-related research product.

Uses

Used in Oncology:
AT9283 is used as an anticancer agent for its ability to inhibit the growth and survival of various solid tumor cell lines. It targets AuroraA/AuroraB and multiple kinases, making it a promising candidate for cancer treatment.
Used in COVID-19 Research:
AT9283 is used as a research product in the context of COVID-19, potentially offering insights into the disease's mechanisms and contributing to the development of therapeutic strategies against the virus.

InChI:InChI=1/C19H23N7O2/c27-19(21-13-2-3-13)24-16-10-20-25-17(16)18-22-14-4-1-12(9-15(14)23-18)11-26-5-7-28-8-6-26/h1,4,9-10,13H,2-3,5-8,11H2,(H,20,25)(H,22,23)(H2,21,24,27)