89660-14-0

Basic information

• Product Name: 2,3-PYRIDINEDIAMINE, 6-CHLORO-N2-METHYL-
• Synonyms: 2,3-PYRIDINEDIAMINE, 6-CHLORO-N2-METHYL-
• CAS NO: 89660-14-0
• Molecular Formula: C₆H₈ClN₃
• Molecular Weight: 157.603
• Mol File: 89660-14-0.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,3-PYRIDINEDIAMINE, 6-CHLORO-N2-METHYL-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-PYRIDINEDIAMINE, 6-CHLORO-N2-METHYL-(89660-14-0)
• EPA Substance Registry System: 2,3-PYRIDINEDIAMINE, 6-CHLORO-N2-METHYL-(89660-14-0)

Safety Data

• Hazardous Substances Data: 89660-14-0(Hazardous Substances Data)

Usage

Description

2,3-Pyridinediamine, 6-Chloro-N2-Methylis a chemical compound with the molecular formula C6H8N4Cl. It is a derivative of pyridine and has a chlorine atom and a methyl group attached to the 6th and N2 positions, respectively. 2,3-PYRIDINEDIAMINE, 6-CHLORO-N2-METHYLis characterized by its potential toxic effects and should be handled with caution due to its potential to cause irritation to the skin, eyes, and respiratory system. Additionally, it may have environmental impacts and should be managed according to safety regulations.

Uses

Used in Pharmaceutical Industry:
2,3-Pyridinediamine, 6-Chloro-N2-Methylis used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of various medicinal compounds. Its unique structure allows it to be a key component in creating drugs with specific therapeutic properties.
Used in Dye Industry:
In the dye industry, 2,3-Pyridinediamine, 6-Chloro-N2-Methylis utilized as an intermediate in the production of dyes. Its chemical structure enables it to be a part of the formulation of dyes that can be used in various applications, such as textiles, plastics, and printing inks.
Used in Organic Compounds Synthesis:
2,3-Pyridinediamine, 6-Chloro-N2-Methylis also used as an intermediate in the synthesis of other organic compounds. Its versatile chemical properties make it a valuable component in the creation of a wide range of organic substances for different industries.

Upstream product

• 33742-70-0 6-chloro-N-methyl-3-nitropyridin-2-amine 
• 16013-85-7 2,6-dicholoro-3-nitropyridine 

Downstream Products

• 89660-20-8 5-chloro-3-methyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 89660-28-6 1-phenyl-3-methyl-5-chloroimidazo<4,5-b>pyridin-2-one 
• 1352420-84-8 2-[1-(cyclopropylmethyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-5-yl]benzonitrile 
• 1352426-22-2 2-(3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-5-yl)benzonitrile 
• 1352421-05-6 2-{3-methyl-1-[(1-methylcyclopropyl)methyl]-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-5-yl}benzonitrile 
• 1352421-07-8 2-{1-[2-fluoro-5-(trifluoromethyl)benzyl]-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-5-yl}benzonitrile 
• 1276673-81-4 N-{1-[1-(2,2-dimethylpropyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-5-yl]-1,2,3,4-tetrahydroquinolin-3-yl}benzamide 
• 1276674-25-9 5-[3-(benzylamino)-3,4-dihydroquinolin-1(2H)-yl]-1-(2,2-dimethylpropyl)-3-methyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1276674-31-7 N-{1-[1-(2,2-dimethylpropyl)-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-5-yl]-1,2,3,4-tetrahydroquinolin-3-yl}-4-methylbenzene-sulfonamide 
• 1276674-41-9 1-(2,2-dimethylpropyl)-3-methyl-5-[5-(phenylcarbonyl)-2,5-diazabicyclo[2.2.2]oct-2-yl]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1276674-51-1 1-(2,2-dimethylpropyl)-3-methyl-5-{5-[(4-methylphenyl)sulfonyl]-2,5-diazabicyclo[2.2.2]oct-2-yl}-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1276675-90-1 1-(2,2-dimethylpropyl)-3-methyl-5-(5-phenyl-2,5-diazabicyclo[2.2.2]oct-2-yl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1276676-15-3 1-(2,2-dimethylpropyl)-3-methyl-5-[9-(phenylcarbonyl)-2,9-diazaspiro[5.5]undec-2-yl]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 
• 1276676-36-8 1-(2,2-dimethylpropyl)-3-methyl-5-[8-(phenylcarbonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one 

Relevant articles and documents

COMBINATIONS COMPRISING BENZODIOXOL AS GLP-1R AGONISTS FOR USE IN THE TREATMENT OF NASH/NAFLD AND RELATED DISEASES

In part, the invention provides a new combination comprising (1) a GLP-1R agonist and (2) an ACC inhibitor or a DGAT2 inhibitor, or a KHK inhibitor or FXR agonist. The invention further provides new methods for treating diseases and disorders, for example, fatty liver, nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, nonalcoholic steatohepatitis with liver fibrosis, nonalcoholic steatohepotitis with cirrhosis, and nonalcoholic steatohepatitis with cirrhosis and with hepatocellular carcinoma or with a metabolic-related disease, obesity, and type 2 diabetes, for example, using the new combination described herein.

GLP-1 RECEPTOR AGONISTS AND USES THEREOF

Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza- benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.

NEW IMIDAZO[4,5-B]PYRIDINE DERIVATIVES AS DUAL DYRK1/CLK1 INHIBITORS

(Formula I) Compounds of formula (I) usefull for the treatment of cancer, neurodegenerative disorders and metabolic disorders.