898283-68-6

Basic information

• Product Name: 2-((2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)oxy)benzaldehyde
• Synonyms: 2-((2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)oxy)benzaldehyde
• CAS NO: 898283-68-6
• Molecular Weight: 452.415
• Mol File: 898283-68-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-((2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)oxy)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)oxy)benzaldehyde(898283-68-6)
• EPA Substance Registry System: 2-((2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)oxy)benzaldehyde(898283-68-6)

Safety Data

• Hazardous Substances Data: 898283-68-6(Hazardous Substances Data)

Upstream product

• 90-02-8 salicylaldehyde 
• 572-09-8 acetobromogalactose 
• 4163-60-4 β-D-galactose peracetate 
• 3068-32-4 1-bromo-2,3,4,6-tetra-O-acetyl-D-galactopyranose 
• 89-95-2 2-methyl-benzyl alcohol 
• 3068-32-4 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside 

Downstream Products

• 959-36-4 salicyaldehyde azine 
• 1365411-53-5 C₃₄H₃₂O₁₅ 
• 1365411-44-4 2-[(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)oxy]benzoic acid 
• 929016-65-9 [2-(hydroxymethyl)phenyl]-2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside 
• 618-65-5 2-β-D-galactopyranosyloxy-benzaldehyde 

Relevant articles and documents

A fluorescent light-up probe based on AIE and ESIPT processes for β-galactosidase activity detection and visualization in living cells

A novel fluorescent probe SA-βGal is reported here with light-up response to β-galactosidase. SA-βGal possesses the β-galactopyranoside group to react with β-galactosidase and releases the fluorescent salicylaldehyde azine with both aggregation induced emission (AIE) and excited-state intramolecular proton transfer (ESIPT) characteristics. The linear fluorescent response enables the in vitro quantification of β-galactosidase activity in a range of 0-0.1 U mL-1 with a detection limit of 0.014 U mL-1. The probe exhibits significant advantages, such as no self-quenching at high concentrations, a large Stokes shift (190 nm) and high specificity to β-galactosidase with an excellent light-up ratio of 820 fold. Moreover, thanks to its good retention in living cells, the application of SA-βGal for the imaging of cellular β-galactosidase was also achieved with high contrast.

COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF

Provided are a compound including a cleavable linker, a use thereof, and an intermediate compound for preparing the same, and more particularly, the compound including a cleavable linker of the present invention may include an active agent (for example, a drug, a toxin, a ligand, a probe for detection, etc.) having a specific function or activity, a SO2 functional group which is capable of selectively releasing the active agent, and a functional group which triggers a chemical reaction, a physicochemical reaction and/or a biological reaction by external stimulation, and may further include a ligand (for example, oligopeptide, polypeptide, antibody, etc.) having binding specificity for a desired target receptor.

Ratiometric electrochemical detection of β-galactosidase

A novel ferrocene-based substrate for the ratiometric electrochemical detection of β-galactosidase was designed and synthesised. It was demonstrated to be an excellent electrochemical substrate for β-Gal detection with sensitivity as low as 0.1 U mL-1.