89978-72-3

Basic information

• Product Name: 4-(broMoMethyl)-2-broMoanisole
• Synonyms: 4-(broMoMethyl)-2-broMoanisole;2-Bromo-4-(bromomethyl)-1-methoxybenzene
• CAS NO: 89978-72-3
• Molecular Formula: C₈H₈Br₂O
• Molecular Weight: 279.95652
• Mol File: 89978-72-3.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(broMoMethyl)-2-broMoanisole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(broMoMethyl)-2-broMoanisole(89978-72-3)
• EPA Substance Registry System: 4-(broMoMethyl)-2-broMoanisole(89978-72-3)

Safety Data

• Hazardous Substances Data: 89978-72-3(Hazardous Substances Data)

Upstream product

• 38493-59-3 (3-bromo-4-methoxy-phenyl)-methanol 
• 22002-45-5 2-bromo-4-methylanisole 
• 34841-06-0 3-bromo-4-methoxybenzylaldehyde 
• 104-93-8 p-methylanizole 
• 35450-37-4 methyl 3-bromo-4-methoxybenzoate 
• 121-98-2 methyl 4-methoxybenzoate 
• 99-96-7 4-hydroxy-benzoic acid 

Downstream Products

• 111210-24-3 2-bromo-1-methoxy-4-(methoxymethyl)benzene 
• 1155877-96-5 1-(4-(3-bromo-4-methoxybenzyl)phenyl)urea 
• 772-59-8 (3-bromo-4-methoxyphenyl)-acetonitrile 
• 1426580-91-7 2-[4-(3-bromo-4-methoxyphenyl)-but-3-enyl]-2-methyl-[1,3]dioxolane 
• 1426580-97-3 2-[4-(3-bromo-4-methoxyphenyl)-but-3-enyl]-2-methyl-[1,3]dioxolane 
• 1155877-97-6 1-(4-((3'-chloro-6-methoxy-[1,1'-biphenyl]-3-yl)methyl)phenyl)urea 

Relevant articles and documents

Homologation of Electron-Rich Benzyl Bromide Derivatives via Diazo C-C Bond Insertion

The ability to manipulate C-C bonds for selective chemical transformations is challenging and represents a growing area of research. Here, we report a formal insertion of diazo compounds into the "unactivated"C-C bond of benzyl bromide derivatives catalyzed by a simple Lewis acid. The homologation reaction proceeds via the intermediacy of a phenonium ion, and the products contain benzylic quaternary centers and an alkyl bromide amenable to further derivatization. Computational analysis provides critical insight into the reaction mechanism, in particular the key selectivity-determining step.

Pyrrolopyrazole derivatives and preparation method thereof, and application of pyrrolopyrazole derivatives in medicines

The invention relates to pyrrolopyrazole derivatives and a preparation method thereof, and application of the pyrrolopyrazole derivatives in medicines. Specifically, the invention relates to novel pyrrolopyrazole derivatives as shown in a general formula (I) in the specification, the preparation method of the pyrrolopyrazole derivatives and application of the pyrrolopyrazole derivatives or pharmaceutical compositions containing the pyrrolopyrazole derivatives as therapeutic agents, particularly as gastric acid secretion inhibitors and potassium ion competitive acid blockers P-CABs) in biological medicines. All the substituents (R1, R2, R3 and R4) and groups (X and Y) in the general formula (I) are as defined in the specification.

COMPOUNDS

A compound of formula (I), or a pharmaceutically acceptable salt thereof.