9007-73-2 Usage
Description
Ferritin, an iron-storage protein, is typically found in the liver and spleen of mammals. It is composed of heavy and light chains and plays a crucial role in the storage and regulation of iron levels in the body. Iron and ferritin are distributed relatively similarly in the eye.
Uses
Used in Biomedical Research:
Ferritin, human is used as a tool for the study of protein synthesis and regulatory mechanisms. It helps researchers understand the processes involved in protein production and regulation within the body.
Used in Microbiology:
Ferritin, cationized from horse spleen, is used to incubate amoebae (106) in studies to determine whether trophozoites can take up ferritin and internalize this protein for their growth in axenic culture. It is also used to determine phagosome-lysosome fusion by electron microscopy.
Used in Neuroscience:
Ferritin from human liver has been used to label freshly excised chick optic tecta in serum-free incubation medium, aiding in the study of neural development and function.
Used in Chromatography Techniques:
Ferritin from human liver serves as a model protein in size-exclusion high-performance liquid chromatography technique, allowing researchers to optimize and evaluate the performance of this separation method.
Used in Nanotechnology:
Ferritin has been utilized in synthetic nanopore translocation studies, providing insights into the behavior of proteins and other molecules at the nanoscale level.
Used in Aquaculture:
Ferritin has been tested for its effect on the susceptibility of shrimp (Litopenaeus vannamei) to the white spot syndrome virus, potentially offering a means to improve disease resistance in aquaculture.
Biochem/physiol Actions
Ferritin holds iron at its ferric state (Fe3+). The core of ferritin?has the capability to hold 4500 iron molecules. It is essential to store iron in vertebrates. Ferritin?is also essential to store and transport iron in invertebrates. It plays a key role in dietary iron absorption.
Purification Methods
The purification of this major iron-binding protein is achieved by homogenisation in water and precipitation with ammonium sulfate, repeating the cycle of ultracentrifugation, and molecular sieve chromatography through a Sephadex 4B column. Isoelectric focusing reveals a broad spectrum of impurities which can be separated by ion-exchange chromatography on Sephadex A-25 and stepwise elution. [Konijn et al. Anal Biochem 144 423 1985.]
Check Digit Verification of cas no
The CAS Registry Mumber 9007-73-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,0 and 7 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 9007-73:
(6*9)+(5*0)+(4*0)+(3*7)+(2*7)+(1*3)=92
92 % 10 = 2
So 9007-73-2 is a valid CAS Registry Number.
