902453-27-4Relevant articles and documents
Catalytic asymmetric synthesis of α,α,α- trifluoromethylamines by the copper-catalyzed nucleophilic addition of diorganozinc reagents to imines
Lauzon, Caroline,Charette, Andre B.
, p. 2743 - 2745 (2006)
A copper-catalyzed asymmetric addition of diorganozinc reagents to N-phosphinoylimines has been developed for the synthesis of chiral α,α,α-trifluoromethylamines. The trifluoromethyl ketimines, generated in situ from the corresponding hemiaminals, led to