9025-42-7
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Basic information
- Product Name: ALPHA-MANNOSIDASE
- Synonyms: ALPHA-MANNOSIDASE;ALPHA-D-MANNOSIDE MANNOHYDROLASE;ALPHA1,6-MANNOSIDASE;ALPHA1-2,3-MANNOSIDASE;EC 3.2.1.24;a1,2-Mannoisdase, Trichodermareesei, Recomb., Saccharomyces;a1,6-Mannosidase, Xanthomonassp., Recomb., E. coli;a1-2,3-Mannosidase, Recomb., E. coli
- CAS NO:9025-42-7
- Molecular Formula:
- Molecular Weight: 0
- EINECS: 232-794-1
- Product Categories: N/A
- Mol File: 9025-42-7.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /buffered aqueous solution
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: N/A
- CAS DataBase Reference: ALPHA-MANNOSIDASE(CAS DataBase Reference)
- NIST Chemistry Reference: ALPHA-MANNOSIDASE(9025-42-7)
- EPA Substance Registry System: ALPHA-MANNOSIDASE(9025-42-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 9025-42-7(Hazardous Substances Data)
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9025-42-7 Usage
Description
ALPHA-MANNOSIDASE, an exo-glycosidase and a metalloenzyme, plays a crucial role in the hydrolysis of terminal, non-reducing alpha-1,2-; alpha-1,3-; alpha-1,6-; and alpha-1,2-mannosyl residues in oligosaccharides. This enzyme is essential for the degradation of complex carbohydrates and glycoproteins, making it a significant component in various biological processes.Uses
Used in Biochemical Research:ALPHA-MANNOSIDASE is used as a research tool for studying the hydrolysis of alpha-mannosyl residues in oligosaccharides and glycoproteins. Its application aids in understanding the structure and function of complex carbohydrates and their role in biological systems.
Used in Pharmaceutical Industry:
ALPHA-MANNOSIDASE is used as an enzyme therapy for the treatment of lysosomal storage disorders, such as mucolipidosis II, where the deficiency of this enzyme leads to the accumulation of undigested glycoproteins and oligosaccharides in the lysosomes.
Used in Neurodegenerative Disease Studies:
ALPHA-MANNOSIDASE is used as a key enzyme in investigating the causes of neurodegeneration in mucolipidosis II 'knock-in' mice. This research helps in understanding the molecular mechanisms underlying the disease and contributes to the development of potential therapeutic strategies.
Used in Food Industry:
ALPHA-MANNOSIDASE is used as a processing aid in the food industry for the modification of carbohydrates in various food products. Its application can improve the texture, flavor, and shelf-life of these products by breaking down complex carbohydrates into simpler forms.
Used in Cosmetic Industry:
ALPHA-MANNOSIDASE is used as an ingredient in cosmetic products for its exfoliating and skin-brightening properties. It helps in the removal of dead skin cells and promotes the synthesis of new cells, resulting in smoother and more radiant skin.
Biochem/physiol Actions
α-Mannosidase is an acid hydrolase which is located in plant vacuoles and is thought to be involved with the turnover of N-linked glycoproteins.Check Digit Verification of cas no
The CAS Registry Mumber 9025-42-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,2 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.Calculate Digit Verification of CAS Registry Number 9025-42:
(6*9)+(5*0)+(4*2)+(3*5)+(2*4)+(1*2)=87
87 % 10 = 7
So 9025-42-7 is a valid CAS Registry Number.
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ALPHA-MANNOSIDASE
