90349-14-7 Usage
General Description
2,5-DIMETHYL-4-NITROBENZIMIDAZOLE is a chemical compound with the molecular formula C9H8N4O2. It is a yellow to orange crystalline solid that is primarily used in the production of dyes, pigments, and pharmaceuticals. The presence of the nitro group in the molecule makes it an important intermediate in the synthesis of various organic compounds. This chemical is known for its potential mutagenic effects and should be handled with care in laboratory settings. Additionally, it is important to follow proper safety protocols and regulations when working with 2,5-DIMETHYL-4-NITROBENZIMIDAZOLE to minimize any potential health hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 90349-14-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,3,4 and 9 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 90349-14:
(7*9)+(6*0)+(5*3)+(4*4)+(3*9)+(2*1)+(1*4)=127
127 % 10 = 7
So 90349-14-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3O2/c1-5-3-4-7-8(9(5)12(13)14)11-6(2)10-7/h3-4H,1-2H3,(H,10,11)
90349-14-7Relevant articles and documents
A novel series of highly potent benzimidazole-based microsomal triglyceride transfer protein inhibitors
Robl,Sulsky,Sun,Simpkins,Wang,Dickson Jr.,Chen,Magnin,Taunk,Slusarchyk,Biller,Lan,Connolly,Kunselman,Sabrah,Jamil,Gordon,Harrity,Wetterau
, p. 851 - 856 (2007/10/03)
A series of benzimidazole-based analogues of the potent MTP inhibitor BMS-201038 were discovered. Incorporation of an unsubstituted benzimidazole moiety in place of a piperidine group afforded potent inhibitors of MTP in vitro which were weakly active in vivo. Appropriate substitution on the benzimidazole ring, especially with small alkyl groups, led to dramatic increases in potency, both in a cellular assay of apoB secretion and especially in animal models of cholesterol lowering. The most potent in this series, 3g (BMS-212122), was significantly more potent than BMS-201038 in reducing plasma lipids (cholesterol, VLDL/LDL, TG) in both hamsters and cynomolgus monkeys.
