90395-44-1

Basic information

• Product Name: Ethanone, 1-[2-(3-pyridinyl)phenyl]-
• CAS NO: 90395-44-1
• Molecular Formula: C13H11NO
• Molecular Weight: 197.236
• Mol File: 90395-44-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[2-(3-pyridinyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[2-(3-pyridinyl)phenyl]-(90395-44-1)
• EPA Substance Registry System: Ethanone, 1-[2-(3-pyridinyl)phenyl]-(90395-44-1)

Safety Data

• Hazardous Substances Data: 90395-44-1(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-[2-(3-pyridinyl)phenyl]- is a chemical compound consisting of a ketone group attached to a phenyl ring bearing a pyridinyl substituent. Ethanone, 1-[2-(3-pyridinyl)phenyl]- belongs to the class of aromatic ketones and is commonly used in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It possesses potential biological activities, including antioxidant, anti-inflammatory, and antiproliferative properties. The presence of the pyridinyl group in this compound enhances its reactivity and binding affinity towards specific biological targets, making it a valuable tool for medicinal chemistry research. Further studies are ongoing to explore the full range of applications and potential uses of this compound in various fields.

Upstream product

• 2142-69-0 2-bromophenyl methyl ketone 
• 89878-14-8 3-Diethylboranylpyridine 
• 864286-95-3 1-[2-(3-pyridyl)phenyl]ethanol 
• 1692-25-7 3-pyridylboronic acid 
• 626-55-1 3-Bromopyridine 
• 308103-40-4 (2-acetylphenyl)boronic acid 
• 59020-10-9 3-(tributylstannyl)pyridine 

Downstream Products

• 206115-43-7 3-(2-acetylphenyl)pyridine 1-oxide 
• 137103-73-2 1-(4-Fluoro-phenyl)-2-imidazol-1-yl-1-(2-pyridin-3-yl-phenyl)-ethanol 
• 57955-12-1 indeno[2,1-b]pyridin-9-one 
• 18631-22-6 5H-indeno[1,2-c]pyridin-5-one 
• 864286-95-3 1-[2-(3-pyridyl)phenyl]ethanol 

Relevant articles and documents

A Straightforward Deracemization of sec-Alcohols Combining Organocatalytic Oxidation and Biocatalytic Reduction

An efficient organocatalytic oxidation of racemic secondary alcohols, mediated by sodium hypochlorite (NaOCl) and 2-azaadamantane N-oxyl (AZADO), has been conveniently coupled with a highly stereoselective bioreduction of the intermediate ketone, catalyzed by ketoreductases, in aqueous medium. The potential of this one-pot two-step deracemization process has been proven by a large set of structurally different secondary alcohols. Reactions were carried out up to 100 mm final concentration enabling the preparation of enantiopure alcohols with very high isolated yields (up to 98 %). When the protocol was applied to the stereoisomeric rac/meso mixture of diols, these were obtained with very high enantiomeric excesses and diastereomeric ratios (95 % yield, >99 % ee, >99: 1 dr).

Efficient diphosphane-based catalyst for the palladium-catalyzed suzuki cross-coupling reaction of 3-pyridylboronic acids

A highly active catalyst system derived from PdCl2 and 2,2',6,6'- tetramethoxy-4,4'-bis(diphenylphosphanyl)-3,3'-bi- pyridine (P-Phos) has been developed for the Suzuki cross- coupling reaction of pyridylboronic acid with a variety of aryl halides in good to excellent yields, even in the presence of hindered and functional groups. In addition, P-Phos also exhibited high activity in the palladium-catalyzed Suzuki reaction of 2,6-dimethoxypyridylboronic acid in excellent yields with a fast rate. The steric and electronic effects of the P- Phos-palladium complex to this cross-coupling reaction were also discussed.

Suzuki coupling reactions of heteroarylboronic acids with aryl halides and arylboronic acids with heteroaryl bromides using a tetraphosphine/palladium catalyst

cix,cis,cis-1,2,3,4-Tetrakis(diphenylphosphinomethyl)cyclopentane/ [PdCl(C3H5)]2 efficiently catalyses the Suzuki reaction of heteroarylboronic acids with aryl bromides and also the coupling of arylboronic acids with heteroaryl bromides. The coupling of thiopheneboronic acids, 3-furanboronic acid and 3-pyridineboronic acid with a variety of aryl bromides gave the corresponding adducts in good yields. However, in most cases, better results in terms of substrate/catalyst ratio were obtained for the reaction of heteroaryl bromides with arylboronic acids. Georg Thieme Verlag Stuttgart.