90719-31-6

Basic information

• Product Name: N-CROTONYL-(4R,5S)-4-METHYL 5-PHENYL-2-OXAZOLIDINONE
• Synonyms: N-CROTONYL-(4R,5S)-4-METHYL 5-PHENYL-2-OXAZOLIDINONE
• CAS NO: 90719-31-6
• Molecular Formula: C₁₄H₁₅NO₃
• Molecular Weight: 245.27
• Product Categories: Peptide
• Mol File: 90719-31-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-CROTONYL-(4R,5S)-4-METHYL 5-PHENYL-2-OXAZOLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: N-CROTONYL-(4R,5S)-4-METHYL 5-PHENYL-2-OXAZOLIDINONE(90719-31-6)
• EPA Substance Registry System: N-CROTONYL-(4R,5S)-4-METHYL 5-PHENYL-2-OXAZOLIDINONE(90719-31-6)

Safety Data

• Hazardous Substances Data: 90719-31-6(Hazardous Substances Data)

Upstream product

• 77943-39-6 4-methyl-5-phenyloxazolidin-2-one 
• 625-35-4 trans-chrotonyl chloride 
• 107-93-7 (E)-but-2-enoic acid 

Downstream Products

• 90719-39-4 (4R,5S)-3-((3'S,4'S,5'R,6'R)-5-methylbicyclo<2.2.1>heptene-4'-carbonyl)-4-methyl-5-phenyl-2-oxazolidinone 
• 108735-20-2 (4R,5S)-3-[(R)-2-((R)-Hydroxy-phenyl-methyl)-but-3-enoyl]-4-methyl-5-phenyl-oxazolidin-2-one 
• 108735-32-6 (4R,5S)-3-((2R,3S)-3-Hydroxy-2-vinyl-pentanoyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 108735-33-7 (4R,5S)-3-((2R,3S)-3-Hydroxy-4-methyl-2-vinyl-pentanoyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 299204-04-9 (4R,5S)-3-{(2R)-2-[(1S)-3-(tert-butyldimethylsilanyloxy)-1-hydroxypropyl]but-3-enoyl}-4-methyl-5-phenyloxazolidin-2-one 
• 299204-06-1 (4R,5S)-3-[(2R,3S)-3-Hydroxy-5-(4-methoxy-benzyloxy)-2-vinyl-pentanoyl]-4-methyl-5-phenyl-oxazolidin-2-one 
• 299204-09-4 (4R,5S)-3-[(2R,3S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-hydroxy-2-vinyl-pentanoyl]-4-methyl-5-phenyl-oxazolidin-2-one 

Relevant articles and documents

Expeditious, large scale preparation of ethyl (R)-5-methyl-3-oxo octanoate via a cross Claisen reaction between N-acyl oxazolidinone derivatives and the magnesium enolate of potassium ethyl malonate

A new and efficient method for the direct conversion of N-acyl oxazolidinones to a β-keto ester is disclosed. The one-pot transformation is effected by the utilization of an excess of Lewis acid along with base and potassium ethyl malonate. This methodology has been applied to the large scale preparation of ethyl (R)-5-methyl-3-oxooctanoate.

A practical method for N-acylation of bornane-2,10-sultam and 2-oxazolidinones

The N-trimethylsilyl derivatives of (+)-bornane-2,10-sultam (10,10-dimethyl-5-thia-4-azatricyclo[5.2.1.03,7]decane 5,5-dioxide) and (R)-4-benzyl-2-oxazolidinone and 4-methyl-5-phenyl-2-oxazolidinone react with acid chlorides in refluxing benzen