90760-98-8Relevant articles and documents
The Crystal Structure of Some 2-Oxo-1,3,2-dioxathiolanes
Lowe, Gordon,Salamone, Salvatore J.,Jones, Richard H.
, p. 262 - 263 (1984)
The trans diastereoisomers of 2-oxo-4(S)-phenyl-1,3,2-dioxathiolane and meso-2-oxo-4,5-diphenyl-1,3,2-dioxathiolane have been unambiguously identified by X-ray analysis; both adopt the half-chair conformation and differential endocyclic S-O bond lengths provide evidence for a stereoelectronic interaction with the S=O group.
Synthesis of Cyclic Sulfite Diesters and their Evaluation as Sulfur Dioxide (SO2) Donors
Malwal, Satish R.,Pardeshi, Kundansingh A.,Chakrapani, Harinath
, p. 1201 - 1205 (2020/02/04)
Although sulfur dioxide (SO2) finds widespread use in the food industry as its hydrated sulfite form, a number of aspects of SO2 biology remain to be completely understood. Of the tools available for intracellular enhancement of SO2 levels, most suffer from poor cell permeability and a lack of control over SO2 release. We report 1,2-cyclic sulfite diesters as a new class of reliable SO2 donors that dissociate in buffer through nucleophilic displacement to produce SO2 with tunable release profiles. We provide data in support of the suitability of these SO2 donors to enhance intracellular SO2 levels more efficiently than sodium bisulfite, the most commonly used SO2 donor for cellular studies.
Ionic Pathways in the Photochemistry of Cyclic Sulfite Esters
White, Rick C.,Arney Jr, Benny E.,Perry, Jacob,Thompson, Nathan,Pithan, Phil M.,von Gradowski, Sebastian,Ihmels, Heiko
, p. 1656 - 1659 (2017/03/27)
The photochemistry of cyclic carbonate esters proceeds by the photochemical extrusion of carbon dioxide to give 1, 3-diradicals which produce oxiranes as well as other radical derived species. The corresponding cyclic sulfite esters, upon irradiation, give intermediates that are trapped by alcohols yet generate no oxiranes. These results are consistent with ionic intermediates.
