90784-34-2

Basic information

• Product Name: N-methyl-N-(2-phenylethyl)formamide
• CAS NO: 90784-34-2
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.2163
• Mol File: 90784-34-2.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 319.9°C at 760 mmHg
• Flash Point: 119.7°C
• Density: 1.021g/cm³
• Vapor Pressure: 0.000329mmHg at 25°C
• Refractive Index: 1.524
• CAS DataBase Reference: N-methyl-N-(2-phenylethyl)formamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-N-(2-phenylethyl)formamide(90784-34-2)
• EPA Substance Registry System: N-methyl-N-(2-phenylethyl)formamide(90784-34-2)

Safety Data

• Hazardous Substances Data: 90784-34-2(Hazardous Substances Data)

Upstream product

• 75-87-6 chloral 
• 589-08-2 N-Methyl-N-phenethylamine 
• 1126-71-2 N,N-dimethylphenethylamine 
• 100-39-0 benzyl bromide 
• 124-38-9 carbon dioxide 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 55246-60-1 methyl-phenethyl-carbamoyl chloride 
• 589-08-2 N-Methyl-N-phenethylamine 
• 1126-71-2 N,N-dimethylphenethylamine 
• 59325-14-3 N--carbaminsaeureaethylester 
• 73355-67-6 N-methyl-N-phenethyl-urea 

Relevant articles and documents

Tetracoordinate borates as catalysts for reductive formylation of amines with carbon dioxide

We report sodium trihydroxyaryl borates as the first robust tetracoordinate organoboron catalysts for reductive functionalization of CO2. These catalysts, easily synthesized from condensing boronic acids with metal hydroxides, activate main group element-hydrogen (E-H) bonds efficiently. In contrast to BX3 type boranes, boronic acids and metal-BAr4 salts, under transition metal-free conditions, sodium trihydroxyaryl borates exhibit high reactivity of reductive N-formylation toward a variety of amines (106 examples), including those with functional groups such as ester, olefin, hydroxyl, cyano, nitro, halogen, MeS-, ether groups, etc. The over-performance to catalyze formylation of challenging pyridyl amines affords a promising alternative method to the use of traditional formylation reagents. Mechanistic investigation supports electrostatic interactions as the key for Si/B-H activation, enabling alkali metal borates as versatile catalysts for hydroborylation, hydrosilylation, and reductive formylation/methylation of CO2.

Method for preparing formamide derivative by using catalyst-free transamination reaction

The invention discloses a method for synthesizing a formamide derivative by using a low-reactive catalyst-free and solvent-free tertiary amide and aliphatic amine transamination reaction, wherein thehigh-yield formamide derivative is obtained by directly using N,N-dimethylformamide (DMF) as a formyl source. According to the present invention, the method has advantages of inexpensive and easily available raw materials, inexpensive and easily available acylating reagent, high reaction yield, one-step reaction, low cost, high reaction selectivity, simple operation and the like, and can overcomethe defects of high toxicity of the reaction reagent, requirement of different types of catalysts, high cost, more reaction steps, more by-products and the like in the prior art.

Method for synthesis of formamide derivatives by cobalt catalysis of formylation reaction

The invention discloses a method for synthesis of formamide derivatives by cobalt catalysis of formylation reaction. The method comprises that the formamide derivatives are produced by one-pot reaction of amine compounds and formamide compounds under the catalysis of cobalt salts; the method has the advantages of cheap and easily obtained reaction raw materials and catalysts, simple reaction stepsand operation, high reaction selectivity, high yield, extendable reaction and the like, and overcomes the defects of high reaction reagent toxicity, expensive catalysts, more reaction steps, more byproducts and the like in the prior art.