908254-94-4Relevant articles and documents
Synthesis and reactivity of imide-derived bisvinyl phosphates. Reactivity of 2,6-disubstituted 1,4-dihydropyridines
Mousset, Deborah,Gillaizeau, Isabelle,Sabatie, Andrea,Bouyssou, Pascal,Coudert, Gerard
, p. 5993 - 5999 (2007/10/03)
Symmetrical and unsymmetrical 2,6-disubstituted dihydropyridines were prepared in high yields under mild conditions using the Suzuki and Stille Pd-catalyzed coupling reactions of imide-derived bisvinyl phosphates with a range of aryl, heteroaryl, and alkenyl moieties. The alkylation reaction at C-4 easily afforded original tri- and tetrasubstituted dihydropyridines. Hydrolysis of the latter under acidic condition provided efficiently either open-chain 1,5-diketones or di- or trisubstituted pyridines.