909391-39-5Relevant articles and documents
Synthesis and SAR studies of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl) acetamide vasopressin V1b receptor antagonists
Napier, Susan E.,Letourneau, Jeffrey J.,Ansari, Nasrin,Auld, Douglas S.,Baker, James,Best, Stuart,Campbell-Wan, Leigh,Chan, Jui-Hsiang,Craighead, Mark,Desai, Hema,Goan, Katharine A.,Ho, Koc-Kan,Hulskotte, Ellen G.J.,MacSweeney, Cliona P.,Milne, Rachel,Morphy, J. Richard,Neagu, Irina,Ohlmeyer, Michael H.J.,Peeters, Ard W.M.M.,Presland, Jeremy,Riviello, Chris,Ruigt, Ge S.F.,Thomson, Fiona J.,Zanetakos, Heather A.,Zhao, Jiuqiao,Webb, Maria L.
, p. 1871 - 1875 (2011)
Synthesis and structure-activity relationships (SAR) of a novel series of vasopressin V1b (V3) antagonists are described. 2-(4-Oxo-2-aryl-quinazolin-3(4H)-yl)acetamides have been identified with low nanomolar affinity for the V1