90942-89-5

Basic information

• Product Name: Cyclohexanecarboxylic acid, 4-(hydroxyimino)-, ethyl ester
• Synonyms: 4-Aethoxycarbonyl-cyclohexanon-oxim;ethyl 4-(hydroxyimino)cyclohexanecarboxylate;4-Ethoxycarbonylcyclohexanone oxime;Cyclohexanecarboxylic acid,4-(hydroxyimino)-,ethyl ester;4-Oximino-cyclohexan-carbonsaeure-(1)-aethylester;4-cyclohexanoneoxime-carboxylic acid ethyl ester
• CAS NO: 90942-89-5
• Molecular Formula: C9H15NO3
• Molecular Weight: 185.223
• Mol File: 90942-89-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarboxylic acid, 4-(hydroxyimino)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxylic acid, 4-(hydroxyimino)-, ethyl ester(90942-89-5)
• EPA Substance Registry System: Cyclohexanecarboxylic acid, 4-(hydroxyimino)-, ethyl ester(90942-89-5)

Safety Data

• Hazardous Substances Data: 90942-89-5(Hazardous Substances Data)

Upstream product

• 17159-79-4 ethyl 4-oxocyclohexane-1-carboxylate 
• 51498-33-0 ethyl 4-amino-1-cyclohexanecarboxylate 
• 64-17-5 ethanol 
• 57555-71-2 4-hydroxyimino-cyclohexanecarboxylic acid 

Downstream Products

• 94-09-7 p-aminoethylbenzoate 
• 1422127-76-1 C₂₃H₂₇F₆N₃O₂S 
• 1422127-62-5 C₂₂H₂₁F₆N₃OS 
• 1422129-62-1 4-((p-toluenesulfonyloxy)imino)cyclohexane-1-carboxylic acid ethyl ester 
• 1422129-65-4 1-[2,4-bis(trifluoromethyl)benzyl]-7-oxoazepane-4-carbaldehyde 
• 1422129-64-3 1-[2,4-bis(trifluoromethyl)benzyl]-5-(hydroxymethyl)azepan-2-one 
• 1422129-63-2 ethyl 1-[2,4-bis(trifluoromethyl)benzyl]-7-oxoazepane-4-carboxylate 
• 1422128-07-1 1-[2,4-bis(trifluoromethyl)benzyl]-5-{(Z)-[2-oxo-4-(prop-2-yn-1-ylamino)-1,3-thiazol-5(2H)-ylidene]methyl}azepan-2-one 
• 1422129-36-9 1-[2,4-bis(trifluoromethyl)benzyl]azepane-4-carbaldehyde 
• 1422129-35-8 {1-[2,4-bis(trifluoromethyl)benzyl]azepan-4-yl}methanol 
• 178312-47-5 ethyl 4,4-difluorocyclohexane-1-carboxylate 
• 95233-40-2 4-fluorocyclohexane-carboxylic acid ethyl ester 
• 17159-79-4 ethyl 4-oxocyclohexane-1-carboxylate 
• 51498-33-0 ethyl 4-amino-1-cyclohexanecarboxylate 

Relevant articles and documents

Cyano-substituted cyclic hydrazine derivatives and application thereof

The invention provides cyano-substituted cyclic hydrazine derivatives. The cyano-substituted cyclic hydrazine derivatives are characterized in that the cyano-substituted cyclic hydrazine derivatives are compounds as shown in the following structural formula shown in the specification or stereoisomers, geometrical isomers, tautomers, racemates, hydrates, solvates, metabolites and pharmaceutically acceptable salts or prodrugs thereof; the compounds are useful for the prevention, treatment, treatment or amelioration of autoimmune diseases or proliferative diseases in patients, and/or for the inhibition or modulation of protein kinase activity.

NITROGEN-CONTAINING HETEROCYCLIC COMPOUND

The present invention provides a novel compound having a superior activity as an ERR-alpha modulator and useful as an agent for the prophylaxis or treatment of ERR-alpha associated diseases. The present invention relates to a compound represented by the formula (1) wherein each symbol is as defined in the specification, or a salt thereof

Dicobaltoctacarbonyl-mediated deoximation

Treatment of oxime O-acetates with Co2(CO)8 in the presence of a base, followed by H2O at room temperature efficiently afforded the parent carbonyl compounds in high yields. Direct regeneration of carbonyl functionalities from the corresponding oxime derivatives was realized by successive exposure to acetylation conditions, Co2(CO)8 in the presence of base, and H2O. In addition, N-monosubstituted hydrazone derivatives could generate the parent carbonyl compound under the above conditions.