909772-67-4 Usage
General Description
"(R)-N-Methyl-2-pyrrolidin-1-ylmethyl-pyrrolidine" is a chemical compound with a molecular formula C11H21N. It is a branched-chain, chiral amine with a pyrrolidine ring structure. R)-N-METHYL-2-PYRROLIDIN-1-YLMETHYL-PYRROLIDINE is commonly used as a pharmaceutical intermediate in the synthesis of various drugs, including antiviral and antipsychotic medications. It is also utilized in organic synthesis, particularly in the production of chiral compounds. Due to its unique structure and properties, (R)-N-Methyl-2-pyrrolidin-1-ylmethyl-pyrrolidine has applications in both the pharmaceutical and chemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 909772-67-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,9,7,7 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 909772-67:
(8*9)+(7*0)+(6*9)+(5*7)+(4*7)+(3*2)+(2*6)+(1*7)=214
214 % 10 = 4
So 909772-67-4 is a valid CAS Registry Number.
909772-67-4Relevant articles and documents
Synthesis of chiral diamines using novel 2-trichloromethyloxazolidin-4-one precursors derived from 5-oxo-proline and proline
Amedjkouh, Mohamed,Ahlberg, Per
, p. 2229 - 2234 (2007/10/03)
Efficient syntheses of chiral vicinal diamines derived from (S)-oxo-proline and (S)-proline are described. The novel diastereomerically pure precursor (2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo-[3.3.0]-octan-4,8-dione 3 and its enantiomer are readily available by reaction of the inexpensive enantiomers of 5-oxo-proline with chloral. Compound 3 reacts with primary and secondary amines to afford the 5-oxo-prolylamides 4 in quantitative yield. In contrast, the (S)-proline-derived precursor (2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo[3.3.0]octan-4-one 6 gave (S)-N-formylprolylamides 9 and/or (S)-prolylamides 8 depending on the reaction conditions. Upon reduction with LiAlH4, amides 4 and 9 afforded the proline-derived (S)-2-(alkylaminomethyl)pyrrolidines 1 and (S)-N-methyl-2-(alkylaminomethyl)-pyrrolidines 5 in 70-90% yields.
