910128-59-5

Basic information

• Product Name: pyridyl disulfide ethyl methacrylate
• CAS NO: 910128-59-5
• Molecular Weight: 255.362
• Mol File: 910128-59-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: pyridyl disulfide ethyl methacrylate(CAS DataBase Reference)
• NIST Chemistry Reference: pyridyl disulfide ethyl methacrylate(910128-59-5)
• EPA Substance Registry System: pyridyl disulfide ethyl methacrylate(910128-59-5)

Safety Data

• Hazardous Substances Data: 910128-59-5(Hazardous Substances Data)

Upstream product

• 2127-03-9 2,2'-dipyridyldisulphide 
• 60-24-2 2-hydroxyethanethiol 
• 920-46-7 Methacryloyl chloride 
• 79-41-4 poly(methacrylic acid) 
• 111625-28-6 2-(2-(Pyridin-2-yl)disulfanyl)ethanol 

Relevant articles and documents

Three-Component Sequential Reactions for Polymeric Nanoparticles with Tailorable Core and Surface Functionalities

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A Pretreatment-Free, Polymer-Based Platform Prepared by Molecular Imprinting and Post-Imprinting Modifications for Sensing Intact Exosomes

Exosomes are small (30–100 nm) membrane vesicles that serve as regulatory agents for intercellular communication in cancers. Currently, exosomes are detected by immuno-based assays with appropriate pretreatments like ultracentrifugation and are time consuming (>12 h). We present a novel pretreatment-free fluorescence-based sensing platform for intact exosomes, wherein exchangeable antibodies and fluorescent reporter molecules were aligned inside exosome-binding cavities. Such antibody-containing fluorescent reporter-grafted nanocavities were prepared on a substrate by well-designed molecular imprinting and post-imprinting modifications to introduce antibodies and fluorescent reporter molecules only inside the binding nanocavities, enabling sufficiently high sensitivity to detect intact exosomes without pretreatment. The effectiveness of the system was demonstrated by using it to discriminate between normal exosomes and those originating from prostate cancer and analyze exosomes in tear drops.

POLYMERIC NANOPARTICLES AND DERIVATIVES THEREOF FOR NUCLEIC ACID BINDING AND DELIVERY

The invention provides polymers and polymeric nanogels in which nucleic acid molecules can be stably entrapped or encapsulated and are controllably delivered and released upon degradation of the nano-structures in response to specific microenvironment triggers, and compositions and methods of preparation and use thereof.