911053-22-0

Basic information

• Product Name: (R)-1-(1-methyl-but-2-ynyl)-pyrrolidine di-p-toluoyl-L-tartaric acid salt
• Synonyms: (R)-1-(1-methyl-but-2-ynyl)-pyrrolidine di-p-toluoyl-L-tartaric acid salt
• CAS NO: 911053-22-0
• Molecular Weight: 523.583
• Mol File: 911053-22-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-(1-methyl-but-2-ynyl)-pyrrolidine di-p-toluoyl-L-tartaric acid salt(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(1-methyl-but-2-ynyl)-pyrrolidine di-p-toluoyl-L-tartaric acid salt(911053-22-0)
• EPA Substance Registry System: (R)-1-(1-methyl-but-2-ynyl)-pyrrolidine di-p-toluoyl-L-tartaric acid salt(911053-22-0)

Safety Data

• Hazardous Substances Data: 911053-22-0(Hazardous Substances Data)

Upstream product

• 911053-21-9 (R)-1-(1-methyl-but-2-ynyl)-pyrrolidine 
• 32634-66-5 Di-p-toluoyl-L-tartaric acid 

Relevant articles and documents

PREPARATION OF OPTICALLY PURE BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN

Disclosed are materials and methods for preparing optically active β-amino acids, which bind to the alpha-2-delta subunit of a calcium channel and are useful for treating pain, fibromyalgia, and a variety of psychiatric and sleep disorders. The method includes reacting a chiral allyl amine with a 2-alkynoate in the presence of a Lewis acid and a base to give a chiral tertiary enamine, which after reaction with ammonia, is hydrogenated to give optically active β-amino acids.