91111-01-2Relevant articles and documents
Hypervalent Iodine(III)-Catalysed Enantioselective α-Acetoxylation of Ketones
Hokamp, Tobias,Wirth, Thomas
supporting information, p. 10417 - 10421 (2020/07/24)
An enantioselective catalytic synthesis of α-acetoxylated ketones through I(I)/I(III) catalysis using a resorcinol/lactamide-based chiral iodoarene is reported. Catalyst turnover by in situ generation of the active iodine(III) derivative is achieved by oxidation with mCPBA in the presence of acetic acid. The prior transformation of ketones to easily accessible acetyl enol ethers is beneficial and yields up to 97 percent with enantioselectivities up to 88 percent ee are obtained using only low catalyst loadings of only 5 mol percent under mild reaction conditions.
Palladium-Catalyzed Oxidative Synthesis of α-Acetoxylated Enones from Alkynes
Jiang, Tuo,Quan, Xu,Zhu, Can,Andersson, Pher G.,B?ckvall, Jan-E.
supporting information, p. 5824 - 5828 (2016/05/09)
We report a palladium-catalyzed oxidative functionalization of alkynes to generate α-acetoxylated enones in one step. A range of functional groups are well-tolerated in this reaction. Mechanistic studies, including the use of 18O-labeled DMSO,
NMR determination of absolute configuration of α-acyloxy ketones
Jullian, Jean-Christophe,Franck, Xavier,Latypov, Shamil,Hocquemiller, Reynald,Figadere, Bruno
, p. 963 - 966 (2007/10/03)
Determination of the absolute configuration of several acyclic α-acyloxy-ketones, and δ-ketobutanolides, in the presence of a chiral solvating agent, by low temperature and low concentration 1H NMR analysis, is reported.