912461-49-5

Basic information

• Product Name: tert-butyl 9-[3-(2-methoxyphenoxy)benzyl]-3,9-diazaspiro[5.5]undecane-3-carboxylate
• Synonyms: tert-butyl 9-[3-(2-methoxyphenoxy)benzyl]-3,9-diazaspiro[5.5]undecane-3-carboxylate
• CAS NO: 912461-49-5
• Molecular Weight: 466.621
• Mol File: 912461-49-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tert-butyl 9-[3-(2-methoxyphenoxy)benzyl]-3,9-diazaspiro[5.5]undecane-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 9-[3-(2-methoxyphenoxy)benzyl]-3,9-diazaspiro[5.5]undecane-3-carboxylate(912461-49-5)
• EPA Substance Registry System: tert-butyl 9-[3-(2-methoxyphenoxy)benzyl]-3,9-diazaspiro[5.5]undecane-3-carboxylate(912461-49-5)

Safety Data

• Hazardous Substances Data: 912461-49-5(Hazardous Substances Data)

Upstream product

• 236406-47-6 3,9-diazaspiro[5.5]undecane-3-carboxylic acid tert-butyl ester hydrochloride 
• 66855-92-3 3-(2-methoxyphenoxy)benzaldehyde 
• 90-05-1 2-methoxy-phenol 
• 87199-16-4 3-Formylphenylboronic acid 
• 173405-78-2 tert-butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate 

Downstream Products

• 912536-38-0 C₂₃H₃₀N₂O₂ 

Relevant articles and documents

Increasing selectivity of CC chemokine receptor 8 antagonists by engineering nondesolvation related interactions with the intended and off-target binding sites

The metabolic stability and selectivity of a series of CCR8 antagonists against binding to the hERGion channel and cytochrome Cyp2D6 are studied by principal component analysis. It is demonstrated that an efficient way of increasing metabolic stability an

NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES

The invention provides compounds of general formula wherein R and R1 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.