91271-62-4

Basic information

• Product Name: [4-(PIPERIDIN-1-YLMETHYL)PHENYL]METHANOL
• Synonyms: [4-(PIPERIDIN-1-YLMETHYL)PHENYL]METHANOL;[4-(Piperidin-1-ylmethyl)phenyl]methanol 95%;4-[(Piperidin-1-yl)methyl]benzyl alcohol 95%;4-[(Piperidin-1-yl)methyl]benzylalcohol95%
• CAS NO: 91271-62-4
• Molecular Formula: C₁₃H₁₉NO
• Molecular Weight: 205.3
• Mol File: 91271-62-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 325.7 °C at 760 mmHg
• Flash Point: 152.1 °C
• Appearance: /
• Density: 1.082 g/cm³
• Vapor Pressure: 9.22E-05mmHg at 25°C
• Refractive Index: 1.57
• PKA: 14.44±0.10(Predicted)
• CAS DataBase Reference: [4-(PIPERIDIN-1-YLMETHYL)PHENYL]METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(PIPERIDIN-1-YLMETHYL)PHENYL]METHANOL(91271-62-4)
• EPA Substance Registry System: [4-(PIPERIDIN-1-YLMETHYL)PHENYL]METHANOL(91271-62-4)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 91271-62-4(Hazardous Substances Data)

Usage

General Description

[4-(piperidin-1-ylmethyl)phenyl]methanol, also known as PMPPM, is an organic compound that belongs to the class of benzyl alcohols. It has the molecular formula C15H21NO and a molar mass of 231.33 g/mol. PMPPM is a colorless liquid at room temperature and is often used as a building block in the synthesis of various pharmaceutical compounds and advanced materials. It is known for its potential pharmacological properties, including its ability to act as a ligand in binding studies. Its unique chemical structure and properties make it valuable for use in medicinal chemistry and related fields.

InChI:InChI=1/C13H19NO/c15-11-13-6-4-12(5-7-13)10-14-8-2-1-3-9-14/h4-7,15H,1-3,8-11H2

Upstream product

• 68453-37-2 4-(piperidinomethyl)benzoic acid methyl ester 
• 110-89-4 piperidine 
• 1571-08-0 methyl 4-formylbenzoate 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 
• 623-27-8 terephthalaldehyde, 

Relevant articles and documents

High-Throughput Screening of Reductive Amination Reactions Using Desorption Electrospray Ionization Mass Spectrometry

This study describes the latest generation of a high-throughput screening system that is capable of screening thousands of organic reactions in a single day. This system combines a liquid handling robot with desorption electrospray ionization (DESI) mass spectrometry (MS) for a rapid reaction mixture preparation, accelerated synthesis, and automated MS analysis. A total of 3840 unique reductive amination reactions were screened to demonstrate the throughputs that are capable with the system. Products, byproducts, and intermediates were all monitored in full-scan mass spectra, generating a complete view of the reaction progress. Tandem mass spectrometry experiments were conducted to verify the identity of the products formed. The amine and electrophile reactivity trends represented in the data match what is expected from theory, indicating that the system accurately models the reaction performance. The DESI results correlated well with those generated using more traditional mass spectrometry techniques like liquid chromatography-mass spectrometry, validating the data generated by the system.

Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds

In an extension of very recently published studies on successful imidazole replacements in some series of histamine H3 receptor antagonists, we report on a new class of lipophilic nonimidazole antagonist having an aliphatic tertiary amino moiet