91407-40-8Relevant articles and documents
Preparation method of fluorine substituted piperidine derivative
-
Paragraph 0021; 0022, (2018/03/24)
The invention discloses a preparation method of a fluorine substituted piperidine derivative of 4-((2-(aminomethyl)-4-fluoro-phenoxybenzyl) methyl)piperidine-1-tert-butyl formate. 5-fluoro-2-hydroxybenzaldehyde is used as a starting raw material to obtain
HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE
-
Page/Page column 40, (2010/12/29)
The present invention provides a novel hydroxyquinoxaline carboxamide derivative that is useful for preventing and/or treating blood coagulation disorders. A compound represented by formula (i), or a pharmacologically acceptable salt thereof: wherein, each of R1 and R2 independently represents a group such as a hydrogen atom or a halogen atom; R3 represents a group such as a hydrogen atom; each of R4 and R5 independently represents a group such as a hydrogen atom, a halogen atom or a C1-4 alkyl group; each of R6 and R7 independently represents a hydrogen atom or a C1-4 alkyl group; X represents a group such as a C3-10 cycloalkyl group, C6-10 aryl group or a 5- to 10-membered heterocyclic group, which may be substituted with substituent(s) selected from substituent group α; Y represents a group such as -CO-, -O- or -NRa-, and Ra represents a group such as a hydrogen atom or a C1-4 alkyl group.
AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE
-
Page/Page column 130-131, (2010/02/14)
A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R 5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.
