914106-86-8Relevant articles and documents
Design and synthesis of novel imidazoline derivatives with potent antihyperglycemic activity in a rat model of type 2 diabetes
Crane, Louis,Anastassiadou, Maria,Hage, Salome El,Stigliani, Jean Luc,Baziard-Mouysset, Genevieve,Payard, Marc,Leger, Jean Michel,Bizot-Espiard, Jean-Guy,Ktorza, Alain,Caignard, Daniel-Henri,Renard, Pierre
, p. 7419 - 7433 (2007/10/03)
Imidazoline derivatives have been reported to show antihyperglycemic activity in vivo. In the present study, we first showed that there was no correlation between the in vivo antidiabetic activity and the in vitro affinities for the I1/I2