914955-62-7Relevant articles and documents
Trisubstituted (E)-alkene dipeptide isosteres as β-turn promoters in the gramicidin S cyclodecapeptide scaffold
Xiao, Jingbo,Weisblum, Bernard,Wipf, Peter
, p. 4731 - 4734 (2007/10/03)
(Chemical Equation Presented) A concise synthesis of a gramicidin S analogue with trisubstituted (E)-alkene dipeptide isostere (TEADI) replacements at both D-Phe-Pro positions was realized. Conformational analysis demonstrated that TEADIs can serve as typ