916501-75-2Relevant articles and documents
A concise approach for the synthesis of bitungolides: Total syntheses of (-)-bitungolide B & e
Reddy, K. Mahender,Shashidhar,Ghosh, Subhash
, p. 4002 - 4012 (2014/06/09)
The first total synthesis of (-)-bitungolide B and a second-generation total synthesis of (-)-bitungolide E are described. The cornerstone of the approach comprises a convergent and flexible route involving Brown crotylation, highly diastereoselective sub
Synthetic studies of microtubule stabilizing agent peloruside A: An asymmetric synthesis of C10-C24 segment
Ghosh, Arun K.,Kim, Jae-Hun
, p. 7659 - 7661 (2007/10/03)
An asymmetric synthesis of the C10-C24 fragment of the potent antitumor macrolide, peloruside A is described. All three stereogenic centers have been enantioselectively constructed utilizing Evans alkylation, Brown asymmetric allylboration, and a substrate controlled epoxide formation. Other key reactions involved Grubbs's ring-closing olefin metathesis and Ando's Z-selective olefination reaction.