916993-95-8Relevant articles and documents
In vitro activity of novel dual action MDR anthranilamide modulators with inhibitory activity at CYP-450
Labrie, Philippe,Maddaford, Shawn. P.,Lacroix, Jacques,Catalano, Concettina,Lee, David K.H.,Rakhit, Suman,Gaudreault, Rene C.
, p. 7972 - 7987 (2007/10/03)
Synthesis and in vitro cytotoxicity assays of new anthranilamide MDR modulators have been performed to assess their inhibition potency of the P-glycoprotein (P-gp) transporter. The aromatic spacer group between nitrogen atoms (N1 and N2/s