918488-41-2 Usage
Description
6-Isoquinolinol, 5-chlorois a chemical compound that belongs to the isoquinolines family. It is a derivative of isoquinolinol with a chlorine atom substituent at the 5-position. 6-Isoquinolinol, 5-chlorohas shown potential pharmacological properties and has been studied for its potential use in pharmaceutical applications. It may be used as a building block in the synthesis of various organic compounds and pharmaceuticals due to its unique structure and reactivity. Additionally, research has suggested that 6-Isoquinolinol, 5-chloromay have antimicrobial and antifungal properties, making it a potential candidate for drug development in these therapeutic areas. Overall, this chemical shows promise for various applications in the pharmaceutical and industrial sectors.
Uses
Used in Pharmaceutical Applications:
6-Isoquinolinol, 5-chlorois used as a building block for the synthesis of various organic compounds and pharmaceuticals. Its unique structure and reactivity make it a valuable component in the development of new drugs.
Used in Antimicrobial Applications:
6-Isoquinolinol, 5-chlorois used as an antimicrobial agent due to its potential to inhibit the growth of certain microorganisms. This property makes it a promising candidate for drug development in the treatment of bacterial infections.
Used in Antifungal Applications:
6-Isoquinolinol, 5-chlorois used as an antifungal agent, showing potential to combat fungal infections. Its effectiveness in this area could lead to the development of new antifungal medications.
Used in Industrial Applications:
6-Isoquinolinol, 5-chloromay also find use in various industrial applications, such as the synthesis of dyes, pigments, and other specialty chemicals, owing to its unique chemical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 918488-41-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,8,4,8 and 8 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 918488-41:
(8*9)+(7*1)+(6*8)+(5*4)+(4*8)+(3*8)+(2*4)+(1*1)=212
212 % 10 = 2
So 918488-41-2 is a valid CAS Registry Number.
918488-41-2Relevant articles and documents
RadH: A Versatile Halogenase for Integration into Synthetic Pathways
Menon, Binuraj R. K.,Brandenburger, Eileen,Sharif, Humera H.,Klemstein, Ulrike,Shepherd, Sarah A.,Greaney, Michael F.,Micklefield, Jason
supporting information, p. 11841 - 11845 (2017/09/20)
Flavin-dependent halogenases are useful enzymes for providing halogenated molecules with improved biological activity, or intermediates for synthetic derivatization. We demonstrate how the fungal halogenase RadH can be used to regioselectively halogenate a range of bioactive aromatic scaffolds. Site-directed mutagenesis of RadH was used to identify catalytic residues and provide insight into the mechanism of fungal halogenases. A high-throughput fluorescence screen was also developed, which enabled a RadH mutant to be evolved with improved properties. Finally we demonstrate how biosynthetic genes from fungi, bacteria, and plants can be combined to encode a new pathway to generate a novel chlorinated coumarin “non-natural” product in E. coli.
CYCLOALKYLAMINE SUBSTITUTED ISOQUINOLINE DERIVATIVES
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Page/Page column 44, (2008/12/06)
The invention relates to 6-substituted isoquinoline derivatives of the Formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
