918658-04-5

Basic information

• Product Name: benzyl 2-amino-4-pyrrolidinothieno[2,3-d]pyrimidine-6-carboxylate
• Synonyms: benzyl 2-amino-4-pyrrolidinothieno[2,3-d]pyrimidine-6-carboxylate
• CAS NO: 918658-04-5
• Molecular Weight: 354.433
• Mol File: 918658-04-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl 2-amino-4-pyrrolidinothieno[2,3-d]pyrimidine-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 2-amino-4-pyrrolidinothieno[2,3-d]pyrimidine-6-carboxylate(918658-04-5)
• EPA Substance Registry System: benzyl 2-amino-4-pyrrolidinothieno[2,3-d]pyrimidine-6-carboxylate(918658-04-5)

Safety Data

• Hazardous Substances Data: 918658-04-5(Hazardous Substances Data)

Upstream product

• 5604-46-6 2-amino-4,6-dichloropyrimidine-5-carboxaldehyde 
• 7383-63-3 mercaptoacetic acid benzyl ester 
• 155087-33-5 2-amino-4-chloro-6-(pyrrolidin-1-yl)pyrimidine-5-carbaldehyde 

Relevant articles and documents

2-Amino-4-pyrrolidinothieno[2,3-d]pyrimidine-6-carboxylic acid as an N-terminal surrogate in amino acid and peptide analogues

2-Amino-4-pyrrolidinothieno[2,3-d]pyrimidine-6-carboxylic acid (4) (ATPC) is an unnatural amino acid with promise in applications as a building block for the synthesis of peptidomimetics. ATPC was obtained from both 3a and 3b thienopyrimidines by hydrolysis and hydrogenolysis, respectively. The synthesis of eleven ATPC-amino acids and two ATPC-peptides is described. ATPC is incorporated as N-terminal moiety in solution or solid-phase peptide synthesis using Boc or Fmoc methodology and without protection of the ATPC amino group. Georg Thieme Verlag Stuttgart.