918896-58-9

Basic information

• Product Name: Benzene, 1-bromo-5-methoxy-2-[(1E)-2-nitroethenyl]-4-(phenylmethoxy)-
• CAS NO: 918896-58-9
• Molecular Formula: C16H14BrNO4
• Molecular Weight: 364.195
• Mol File: 918896-58-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, 1-bromo-5-methoxy-2-[(1E)-2-nitroethenyl]-4-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-bromo-5-methoxy-2-[(1E)-2-nitroethenyl]-4-(phenylmethoxy)-(918896-58-9)
• EPA Substance Registry System: Benzene, 1-bromo-5-methoxy-2-[(1E)-2-nitroethenyl]-4-(phenylmethoxy)-(918896-58-9)

Safety Data

• Hazardous Substances Data: 918896-58-9(Hazardous Substances Data)

Upstream product

• 621-59-0 isovanillin 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 2973-59-3 2-bromoisovanillin 
• 75-52-5 nitromethane 
• 6451-86-1 5-benzyloxy-2-bromo-4-methoxybenzaldehyde 

Downstream Products

• 160857-70-5 (3-benzyloxy-6-bromo-4-methoxyphenethylimino)triphenylphosphorane 
• 160857-67-0 8-benzyloxy-5-bromo-7-methoxy-1-(3-nitro-4-methoxybenzyl)-3,4-dihydroisoquinoline 
• 158837-95-7 8-Benzyloxy-7-methoxy-1-(4-methoxy-3-nitro-benzyl)-3,4-dihydro-isoquinoline 
• 158837-97-9 1-(3-Azido-4-methoxy-benzyl)-8-benzyloxy-7-methoxy-3,4-dihydro-isoquinoline 
• 160857-66-9 5-bromo-8-benzyloxy-1-(3,4-dimethoxybenzyl)-7-methoxy-3,4-dihydroisoquinoline 
• 158837-99-1 8-Benzyloxy-1-(3,4-dimethoxy-benzyl)-7-methoxy-3,4-dihydro-isoquinoline 
• 158837-96-8 5-(8-Benzyloxy-7-methoxy-3,4-dihydro-isoquinolin-1-ylmethyl)-2-methoxy-phenylamine 
• 697803-46-6 1-(3,4-Dimethoxy-benzyl)-7-methoxy-3,4-dihydro-isoquinolin-8-ol 
• 479-39-0 (+)-cularine 
• 104420-84-0 (+)-Enneaphylline 
• 918896-64-7 6-benzyloxy-1-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-7-methoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 918896-61-4 2-[2-(ethylpropionate)-4-methoxy-5-benzyloxy]-1-(tert-butoxycarbonyl-amino)-ethane 
• 918896-62-5 6-benzyloxy-1-ethoxycarbonylmethyl-7-methoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 918896-63-6 6-benzyloxy-1-(2-hydroxy-ethyl)-7-methoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 

Relevant articles and documents

Synthetic studies on Ecteinascidin-743: synthesis of building blocks through Sharpless asymmetric dihydroxylation and aza-Michael reactions

A practical and an efficient synthesis of three building blocks of tetrahydroisoquinoline alkaloid Ecteinascidin-743 was accomplished, starting from readily available piperonal, 2-methyl anisole, and veratraldehyde. A combination of Vilsmeier-Haack reaction and Sharpless asymmetric dihydroxylation was employed for the synthesis of building blocks A and B whereas a Heck reaction in PEG-2000 and aza-Michael reactions were employed for the synthesis of building block C.