919103-31-4

Basic information

• Product Name: (R)-BoroAla(+)-Pinanediol-HCl
• Synonyms: (R)-BoroAla(+)-Pinanediol-HCl;(R)-BoroAla(+)-Pinanediol-hydrochloride;(R)-Boroalanine-(+)-pinanediol-HCl;(R)-Boroalanine-(+)-pinanediola€￠HCl
• CAS NO: 919103-31-4
• Molecular Formula: C12H23BClNO2
• Molecular Weight: 259.58052
• Mol File: 919103-31-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-BoroAla(+)-Pinanediol-HCl(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-BoroAla(+)-Pinanediol-HCl(919103-31-4)
• EPA Substance Registry System: (R)-BoroAla(+)-Pinanediol-HCl(919103-31-4)

Safety Data

• Hazardous Substances Data: 919103-31-4(Hazardous Substances Data)

Usage

Description

(R)-BoroAla(+)-Pinanediol-HCl is a chiral compound formed by the combination of (R)-BoroAla, a boron-containing amino acid derivative, and (+)-Pinanediol hydrochloride. It has potential applications in the pharmaceutical and chemical industries due to its unique properties and the ability to be used in the synthesis of various chiral pharmaceuticals and organic compounds.
Used in Pharmaceutical Industry:
(R)-BoroAla(+)-Pinanediol-HCl is used as a chiral building block for the synthesis of chiral pharmaceuticals and organic compounds. Its unique properties and the presence of boron and chiral centers make it a valuable compound for the development of new drugs and pharmaceutical agents.
Used in Chemical Industry:
(R)-BoroAla(+)-Pinanediol-HCl is used as a chiral reagent in the synthesis of various organic compounds. Its ability to form chiral centers and its unique properties make it a useful compound for the development of new chemical processes and the production of enantiomerically pure compounds.

Upstream product

• 87247-50-5 C₇H₇BO₂(CH₃)3(CHClCH₃) 
• 18680-27-8 pinanediol 
• 7785-70-8 (+)-α-pinene 
• 84110-38-3 (1S,2S,3R,5S)-2α,3α-pinanediol methylboronic ester 
• 85167-12-0 (+)-pinanediol (1S)-1-chloro-1-ethaneboronate 
• 132562-10-8 methylboronic acid pinanediol ester 
• 497165-15-8 D-1-(aminoethyl)boronic acid pinanediol ester 
• 53404-49-2 2,3-trans-pinanediol 
• 1313706-65-8 C₁₈H₃₈BNO₂Si₂ 

Downstream Products

• 1451205-23-4 C₄₂H₆₁BClN₇O₇ 

Relevant articles and documents

BETA-LACTAMASE INHIBITORS

Disclosed herein inter alia are Boron containing compounds and methods for treating infections related to antibiotic resistant microorganisms.

Crystal structure of a complex between the actinomadura R39 dd -peptidase and a peptidoglycan-mimetic boronate inhibitor: Interpretation of a transition state analogue in terms of catalytic mechanism

The Actinomadura R39 dd-peptidase is a bacterial low molecular weight class C penicillin-binding protein. It has previously been shown to catalyze hydrolysis and aminolysis of small d-alanyl-d-alanine terminating peptides, especially those with a side cha

Boro-norleucine as a P1 residue for the design of selective and potent DPP7 inhibitors

Dipeptide-based inhibitors with C-substituted (alkyl or aminoalkyl) α-amino acids in the P2 position and boro-norleucine (boro-Nle) in the P1 position were synthesized. Relative to boro-proline, boro-Nle as a P1 residue was shown able to significantly dial out DPP4, FAP, DPP8, and DPP9 activity. Dab-boro-Nle (4g) proved to be the most selective and potent DPP7 inhibitor with a DPP7 IC50 value of 480 pM.