919530-03-3

Basic information

• Product Name: 4H-1,3-Oxazin-4-one, tetrahydro-5-(phenylthio)-6-(2-thienyl)-2-[(1S)-1-[[tris(1-methylethyl)silyl] oxy]ethyl]-, (2S,5S,6S)-
• CAS NO: 919530-03-3
• Molecular Formula: C25H37NO3S2Si
• Molecular Weight: 491.791
• Mol File: 919530-03-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4H-1,3-Oxazin-4-one, tetrahydro-5-(phenylthio)-6-(2-thienyl)-2-[(1S)-1-[[tris(1-methylethyl)silyl] oxy]ethyl]-, (2S,5S,6S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,3-Oxazin-4-one, tetrahydro-5-(phenylthio)-6-(2-thienyl)-2-[(1S)-1-[[tris(1-methylethyl)silyl] oxy]ethyl]-, (2S,5S,6S)-(919530-03-3)
• EPA Substance Registry System: 4H-1,3-Oxazin-4-one, tetrahydro-5-(phenylthio)-6-(2-thienyl)-2-[(1S)-1-[[tris(1-methylethyl)silyl] oxy]ethyl]-, (2S,5S,6S)-(919530-03-3)

Safety Data

• Hazardous Substances Data: 919530-03-3(Hazardous Substances Data)

Upstream product

• 98-03-3 thiophene-2-carbaldehyde 

Downstream Products

• 116539-55-0 (S)-3-methylamino-1-(2-thienyl)-1-propanol 

Relevant articles and documents

5-Phenylthio-1,3-oxazinan-4-ones via hetero Diels-Alder reactions: synthesis of (R)- and (S)-Duloxetines and Fluoxetines

The synthesis of 5-phenylthio-1,3-oxazinan-4-ones, through a hetero Diels-Alder strategy, is described. The cycloadducts thus prepared have been shown to be useful intermediates for the synthesis of 1,3-aminoalcohols, valuable intermediates in the preparation of biologically significant molecules, e.g., optically active Duloxetines and Fluoxetines. In the course of this elaboration a novel microwave assisted desulfurization reaction is reported.