92-07-9

Basic information

• Product Name: 3,5-DIPHENYLPYRIDINE
• Synonyms: Pyridine, 3,5-diphenyl-;3,5-DIPHENYLPYRIDINE
• CAS NO: 92-07-9
• Molecular Formula: C17H13N
• Molecular Weight: 231.29
• EINECS: 202-123-7
• Mol File: 92-07-9.mol
• Article Data: 39

Chemical Properties

• Melting Point: 193-194 °C
• Boiling Point: 395.6°C at 760 mmHg
• Flash Point: 175.3°C
• Appearance: /
• Density: 1.084g/cm³
• Vapor Pressure: 4.15E-06mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.47±0.20(Predicted)
• CAS DataBase Reference: 3,5-DIPHENYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIPHENYLPYRIDINE(92-07-9)
• EPA Substance Registry System: 3,5-DIPHENYLPYRIDINE(92-07-9)

Safety Data

• Hazardous Substances Data: 92-07-9(Hazardous Substances Data)

Usage

General Description

3,5-Diphenylpyridine is a chemical compound with the molecular formula C17H13N. It is a heterocyclic aromatic compound that is commonly used in organic synthesis and as a building block for the preparation of various pharmaceuticals and agrochemicals. 3,5-Diphenylpyridine is known for its unique structure and its ability to act as a ligand for transition metal catalysts, making it valuable in catalytic processes. It is also used in the production of dyes and pigments, as well as in the development of new materials such as polymers and liquid crystals. Additionally, 3,5-Diphenylpyridine has been studied for its potential biological activities, including its antimicrobial and anticancer properties.

InChI:InChI=1/C17H13N/c1-3-7-14(8-4-1)16-11-17(13-18-12-16)15-9-5-2-6-10-15/h1-13H

Upstream product

• 408313-19-9 3,5-Diphenyl-piperidine 
• 101605-25-8 3,5-diphenyl-pyridine-2-carboxylic acid 
• 122-78-1 phenylacetaldehyde 
• 78-84-2 isobutyraldehyde 
• 90921-81-6 N-methoxycarbonyl-2-phenylethenylamine 
• 71-43-2 benzene 
• 36838-59-2 N-styrylmorpholine 
• 10560-39-1 1,3,5-tri-tert-butyl-1,3,5-triazacyclohexane 
• 24903-95-5 nopinone 
• 7089-34-1 ((E)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate 
• 108-94-1 cyclohexanone 
• 7089-34-1 ((Z)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate 
• 13987-61-6 N-methylene-tert-butylamine 
• 123-72-8 butyraldehyde 

Downstream Products

• 109726-74-1 1-methyl-3,5-diphenyl-pyridinium; iodide 

Relevant articles and documents

Use of highly reactive, versatile and air-stable palladium-phosphinous acid complex [(t-Bu)2P(OH)]2PdCl2 (POPd) as a catalyst for the optimized Suzuki-Miyaura cross-coupling of less reactive heteroaryl chlorides and arylboronic acids

Using highly reactive air-stable palladium-phosphinous acid complex [(t-Bu)2P(OH)]2PdCl2 (POPd) as a catalyst, synthesis of heteroaryl-aryl cross-coupled products via palladium-catalyzed Suzuki-Miyaura coupling of less reactive substituted 3-chloropyridines with arylboronic acids was achieved in high yields.

Selective Synthesis of Substituted Pyridines and Pyrimidines through Cascade Annulation of Isopropene Derivatives

Diverse substituted pyridines and pyrimidines with high selectivity were obtained using a concise and efficient protocol developed herein. The reaction proceeds via metal-free cascade annulation of isopropene derivatives. Using isopropene derivatives as C3 synthons, NH4I as the “N” source, and formaldehyde or dimethyl sulfoxide as the carbon source, this reaction realizes the efficient formation of intermolecular C-N and C-C bonds.

Base-promoted one-pot synthesis of pyridine derivatives via aromatic alkyne annulation using benzamides as nitrogen source

In the presence of Cs2CO3, the first simple, efficient, and one-pot procedure for the synthesis of 3,5-diaryl pyridines via a variety of aromatic terminal alkynes with benzamides as the nitrogen source in sulfolane is described. The formation of pyridine derivatives accompanies the outcome of 1,3-diaryl propenes, which are also useful intermediates in organic synthesis. Thus, pyridine ring results from a formal [2+2+1+1] cyclocondensation of three alkynes with benzamides, and one of the alkynes provides one carbon, whilst benzamides provide a nitrogen source only. A new transformation of alkynes as well as new utility of benzamide are found in this work.

Method for constructing 3,5-disubstituted pyridine from aryl ethylene and N,N-dimethylformamide through cyclization reaction

The invention discloses a method for constructing 3,5-disubstituted pyridine from aryl ethylene and N,N-dimethylformamide through a cyclization reaction. The method comprises carrying out cyclizationon the aryl ethylene, the N,N-dimethylformamide and peroxydisulfate under the catalytic action of iodized salt to obtain the 3,5-disubstituted pyridine. According to the method, iodine salt is utilized to catalyze one-step oxidative cyclization of the aryl ethylene and DMF to synthesize 3,5-disubstituted pyridine, and the method has the advantages of low cost of raw materials and catalysts, mild reaction conditions, capability of obtaining symmetric 3,5-disubstituted pyridine with high selectivity and high yield and the like.