92008-51-0 Usage
Description
5(S)-HEPE, also known as 5-Hydroxyeicosapentaenoic acid, is a bioactive lipid mediator derived from the metabolism of eicosapentaenoic acid (EPA) through the action of 5-lipoxygenase enzyme. It is structurally similar to leukotrienes and has been implicated in various biological processes, although its specific functions and mechanisms of action are not well understood.
Uses
Used in Pharmaceutical Industry:
5(S)-HEPE is used as a potential therapeutic agent for various inflammatory and immune-related disorders due to its anti-inflammatory and immunomodulatory properties. It has been shown to modulate the production of pro-inflammatory mediators and cytokines, as well as influence the activity of immune cells, making it a promising candidate for the treatment of conditions such as asthma, rheumatoid arthritis, and inflammatory bowel disease.
Used in Research Applications:
5(S)-HEPE is used as a research tool for studying the role of eicosanoids in various physiological and pathological processes. It is commonly used in in vitro and in vivo experiments to investigate the mechanisms of action of 5-lipoxygenase and its products, as well as to explore the potential therapeutic effects of 5(S)-HEPE in different disease models.
Check Digit Verification of cas no
The CAS Registry Mumber 92008-51-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,0,0 and 8 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 92008-51:
(7*9)+(6*2)+(5*0)+(4*0)+(3*8)+(2*5)+(1*1)=110
110 % 10 = 0
So 92008-51-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(21)17-15-18-20(22)23/h3-4,6-7,9-10,12-14,16,19,21H,2,5,8,11,15,17-18H2,1H3,(H,22,23)/b4-3-,7-6-,10-9-,13-12-,16-14+
92008-51-0Relevant articles and documents
Synthesis of 5-(S)-HETE, 5-(S)-HEPE and (+)-zooxanthellactone: Three hydroxylated polyunsaturated fatty acid metabolites
Primdahl, Karoline Gangestad,Stenstr?m, Yngve,Hansen, Trond Vidar,Vik, Anders
, p. 1 - 4 (2016/02/19)
Short and stereoselective syntheses of the two hydroxylated polyunsaturated fatty acid metabolites, namely 5-(S)-HETE and 5-(S)-HEPE, are reported in 23% and 30% overall yields, respectively. In addition, synthesis of the polyunsaturated fatty acid natura
Synthesis of polyconjugated fatty acids
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Page 3; 12, (2010/02/10)
The present invention relates to fatty acids. In particular, the present invention provides polyconjugated fatty acids, and methods of their synthesis and their use.
