92089-09-3

Basic information

• Product Name: Furo[3,4-b]pyridine-3-carboxylic acid, 1,4,5,7-tetrahydro-2-methyl-4-(2-nitrophenyl)-5-oxo-, methyl ester
• Synonyms: hydroxy-dehydronifedipin;2-methyl-3-methoxycarbonyl-5-oxo-4-(o-nitrophenyl)-1,4,5,7-tetrahydrofuro(3,4-b)pyridine;methyl 2-methyl-4-(2-nitrophenyl)-5-oxo-1,4,5,7-tetrahydrofuro[3,4-b]pyridine-3-carboxylate
• CAS NO: 92089-09-3
• Molecular Formula: C16H14N2O6
• Molecular Weight: 330.297
• Mol File: 92089-09-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Furo[3,4-b]pyridine-3-carboxylic acid, 1,4,5,7-tetrahydro-2-methyl-4-(2-nitrophenyl)-5-oxo-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Furo[3,4-b]pyridine-3-carboxylic acid, 1,4,5,7-tetrahydro-2-methyl-4-(2-nitrophenyl)-5-oxo-, methyl ester(92089-09-3)
• EPA Substance Registry System: Furo[3,4-b]pyridine-3-carboxylic acid, 1,4,5,7-tetrahydro-2-methyl-4-(2-nitrophenyl)-5-oxo-, methyl ester(92089-09-3)

Safety Data

• Hazardous Substances Data: 92089-09-3(Hazardous Substances Data)

Upstream product

• 552-89-6 2-nitro-benzaldehyde 
• 14205-39-1 methyl (E)-3-aminocrotonate 
• 87191-97-7 3-<(2-Nitrophenyl)methylene>-2,4(3H,5H)-furandione 
• 21829-25-4 nifedipine 
• 39416-48-3 pyridinium hydrobromide perbromide 
• 110-86-1 pyridine 

Downstream Products

• 195821-11-5 2-Methyl-4-(2-nitroso-phenyl)-5-oxo-5,7-dihydro-furo[3,4-b]pyridine-3-carboxylic acid methyl ester 
• 34785-00-7 2-Methyl-4-(2-nitrophenyl)-5-oxo-5,7-dihydrofuro<3,4-b>pyridin-3-carbonsaeuremethylester 

Relevant articles and documents

EX VIVO METHODS FOR PREDICTING AND CONFIRMING IN VIVO METABOLISM OF PHARMACEUTICALLY ACTIVE COMPOUNDS

Methods and compositions for the catalytic oxidation of pharmaceutically active compounds, and more particularly to ex vivo methods for predicting in vivo metabolism of pharmaceutically active compounds, including predicting in vivo interaction between two or more pharmaceutically active compounds.

Cyclic hydroxamic acids of the phenanthridine type - Synthesis and investigation of lipoxigenase inhibition

The synthesis of the benzo[f]furo[3,4-c] [2,7]naphthyridines 15 and 17, the thieno[2,3-c] [2,7]naphthyridines 21 as well as the pyrimido[5,4-c]quinoline 25 is described. These compounds and the structurally related diaza- and triaza-phenanthrenes 3-8 were

FORMATION OF FURO- AND DIFURO-1,4-DIHYDROPYRIDINES IN THE BROMINATION OF 2,6-DIMETHYL-3,5-DIMETHOXYCARBONYL-4-(o-NITROPHENYL)-1,4-DIHYDROPYRIDINE

Furo- and difuro-1,4-dihydropyridines were obtained by bromination of 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(o-nitrophenyl)-1,4-dihydropyridine with mild brominating agents (pyridinium bromide perbromide, N-bromosuccinimide, and dioxane dibromide).