92145-32-9 Usage
Description
3-Ethoxy-2-methyl-2-propenoic acid ethyl ester, also known as Ethyl 3-Ethoxy-2-methylpropyl-2-enoate, is an organic compound that serves as a key reactant in the synthesis of various pharmaceutical agents. It is characterized by its ester functional group and a unique ethoxymethylpropyl side chain, which contributes to its reactivity and potential applications in medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
3-Ethoxy-2-methyl-2-propenoic acid ethyl ester is used as a reactant in the synthesis of kinase inhibitors for anti-cancer applications. Its unique structure allows it to be incorporated into the design of potent and selective inhibitors targeting specific kinases involved in cancer cell proliferation and survival.
Specifically, it is utilized in the development of anti-cancer agents such as staurosporine and EKB-509. These kinase inhibitors have demonstrated the ability to interfere with the activity of various protein kinases, thereby inhibiting the growth and spread of cancer cells. The use of 3-Ethoxy-2-methyl-2-propenoic acid ethyl ester in the synthesis of these compounds highlights its importance in the discovery and production of novel cancer therapeutics.
Check Digit Verification of cas no
The CAS Registry Mumber 92145-32-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,1,4 and 5 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 92145-32:
(7*9)+(6*2)+(5*1)+(4*4)+(3*5)+(2*3)+(1*2)=119
119 % 10 = 9
So 92145-32-9 is a valid CAS Registry Number.
92145-32-9Relevant articles and documents
PYRROLO[1,2-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS
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Paragraph 00369, (2017/11/04)
The invention provides substituted pyrrolo[1,2-a]pyrimidinyl carboxamide and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted pyrrolo[1,2-a]pyrimidinyl carboxamide compounds described herein include substituted 2-heterocyclyl-4-alkyl-pyrrolo[1,2-a]pyrimidine-8-carboxarnide compounds and variants thereof.
COMPOUNDS AND METHODS FOR ANTIVIRAL TREATMENT
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Paragraph 0412-0413, (2013/10/22)
Compounds and pharmaceutically acceptable salts and esters and compositions thereof, for treating viral infections are provided. The compounds and compositions are useful for treating Pneumovirinae virus infections. The compounds, compositions, and methods provided are particularly useful for the treatment of Human respiratory syncytial virus infections