92159-87-0

Basic information

• Product Name: benzyl 4-bromophenylcarbamate
• Synonyms: benzyl 4-bromophenylcarbamate;Benzyl N-(4-broMophenyl)carbaMate;N-Cbz-4-bromoaniline
• CAS NO: 92159-87-0
• Molecular Formula: C₁₄H₁₂BrNO₂
• Molecular Weight: 306.15458
• Mol File: 92159-87-0.mol
• Article Data: 20

Chemical Properties

• Melting Point: 121-123 °C
• Boiling Point: 367.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.487±0.06 g/cm3(Predicted)
• PKA: 12.93±0.70(Predicted)
• CAS DataBase Reference: benzyl 4-bromophenylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 4-bromophenylcarbamate(92159-87-0)
• EPA Substance Registry System: benzyl 4-bromophenylcarbamate(92159-87-0)

Safety Data

• Hazardous Substances Data: 92159-87-0(Hazardous Substances Data)

Usage

Description

Benzyl 4-bromophenylcarbamate is a chemical compound synthesized from the reaction between benzylamine and 4-bromophenyl isocyanate. It is a white to pale yellow solid at room temperature, slightly soluble in water, and more soluble in organic solvents. benzyl 4-bromophenylcarbamate is relatively stable under normal conditions and does not pose a significant risk to health or the environment when handled and stored properly.

Uses

Used in Polymer Production:
Benzyl 4-bromophenylcarbamate is used as a crosslinking agent in the production of polymers, enhancing their structural integrity and performance characteristics.
Used in Plastics Processing:
Benzyl 4-bromophenylcarbamate serves as a stabilizer in the processing of plastics, improving their durability and resistance to degradation.
Used in Pharmaceutical Synthesis:
Benzyl 4-bromophenylcarbamate is utilized in the synthesis of pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Organic Chemistry:
Benzyl 4-bromophenylcarbamate acts as a reagent in organic chemistry reactions, facilitating various chemical processes and transformations.

Upstream product

• 501-53-1 benzyl chloroformate 
• 106-40-1 4-bromo-aniline 
• 14917-59-0 p-bromobenzoyl azide 
• 100-51-6 benzyl alcohol 
• 586-76-5 4-Bromobenzoic acid 
• 3422-03-5 benzyloxycarbonyl azide 
• 5467-74-3 4-Bromophenylboronic acid 
• 621-84-1 O-benzyl carbamate 
• 589-87-7 1,4-bromoiodobenzene 
• 698-67-9 p-bromobenzamide 
• 124-38-9 carbon dioxide 
• 100-39-0 benzyl bromide 
• 104-57-4 benzyl formate 
• 131818-17-2 tert-butyl (4-bromophenyl)carbamate 

Downstream Products

• 71150-68-0 benzyl N-(4-formylphenyl)carbamate 
• 959939-45-8 benzyl ((4-(1,4-dioxaspiro)[4.5] dec-7-en-8-yl)phenyl)carbamate 
• 947170-99-2 benzyl 4-bromophenyl(methyl)carbamate 
• 947171-10-0 C₂₃H₂₈NPO₈ 
• 947171-00-8 (4-(N-benzyloxycarbonyl-N-methylamino)phenyl)phosphinic acid 
• 777089-57-3 methyl (2E)-3-(4-{[(benzyloxy)carbonyl]amino}phenyl)acrylate 
• 777089-58-4 benzyl 4-[(1E)-3-hydroxyprop-1-enyl]phenylcarbamate 
• 777089-62-0 [(1S,5R,6S)-4-(3-Oxa-bicyclo[3.1.0]hex-6-yl)-phenyl]-carbamic acid benzyl ester 
• 777089-67-5 [(1S,5R,6S)-4-(3-Thia-bicyclo[3.1.0]hex-6-yl)-phenyl]-carbamic acid benzyl ester 
• 777089-59-5 (2E)-3-{4-[((benzyloxy)carbonyl)amino]phenyl}prop-2-enyl diazoacetate 
• 777089-61-9 [4-((1S,2R,3S)-2,3-Bis-hydroxymethyl-cyclopropyl)-phenyl]-carbamic acid benzyl ester 
• 777089-64-2 {4-[(1S,5R,6S)-3-(4-Methoxy-benzyl)-3-aza-bicyclo[3.1.0]hex-6-yl]-phenyl}-carbamic acid benzyl ester 
• 881012-64-2 Methanesulfonic acid (1S,2S,3R)-2-(4-benzyloxycarbonylamino-phenyl)-3-methanesulfonyloxymethyl-cyclopropylmethyl ester 
• 937737-97-8 C₁₆H₁₅NO₃S 

Relevant articles and documents

Visible light-induced mono-bromination of arenes with BrCCl3

A highly efficient and regioselective bromination of electron-rich arenes and heteroarenes using commercially available BrCCl3as a “Br” source has been developed. The reaction was performed in air under mild conditions with photocatalyst Ru(bpy)3Cl2·6H2O, avoiding the usage of strong acids and strong oxidants. Mono-brominated products were obtained with medium to excellent yields (up to 94%). This strategy has shown good compatibility and highpara-selectivity, which will facilitate the complicated synthesis.

Pyrazolone-fused pyrimidine compound as well as preparation method and application thereof

The invention discloses a pyrazolone-fused pyrimidine compound as well as a preparation method and application thereof. The invention provides a pyrazolone-fused pyrimidine compound as shown in a formula I which is described in the specification. The pyrazolone-fused pyrimidine compound has better inhibitory activity on WEE1 kinase.

One stone two birds: Cobalt-catalyzed in situ generation of isocyanates and benzyl alcohols for the synthesis of N-aryl carbamates

An efficient method for the synthesis of N-aryl carbamates from N-Boc-protected amines has been developed. The cobalt-catalyzed in situ generation of isocyanates from N-Boc-protected amines and benzyl alcohols from benzyl formates has been achieved for the first time, which in turn furnished the corresponding benzyl carbamates in moderate to high yields. The reaction was catalyzed by CoI2 with tris-(4-dimethylaminophenyl)-phosphine as the ligand and zinc powder as the reductant. The developed reaction conditions were found to be compatible for aromatic amines with both electron-donating and -withdrawing substituents.