922173-25-9

Basic information

• Product Name: (2S,3S,4S,5R,6S)-3,4,5-Tris-allyloxycarbonyloxy-6-[4-(tert-butyl-dimethyl-silanyloxymethyl)-phenylcarbamoyloxy]-tetrahydro-pyran-2-carboxylic acid allyl ester
• Synonyms: (2S,3S,4S,5R,6S)-3,4,5-Tris-allyloxycarbonyloxy-6-[4-(tert-butyl-dimethyl-silanyloxymethyl)-phenylcarbamoyloxy]-tetrahydro-pyran-2-carboxylic acid allyl ester
• CAS NO: 922173-25-9
• Molecular Weight: 749.841
• Mol File: 922173-25-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S,4S,5R,6S)-3,4,5-Tris-allyloxycarbonyloxy-6-[4-(tert-butyl-dimethyl-silanyloxymethyl)-phenylcarbamoyloxy]-tetrahydro-pyran-2-carboxylic acid allyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,4S,5R,6S)-3,4,5-Tris-allyloxycarbonyloxy-6-[4-(tert-butyl-dimethyl-silanyloxymethyl)-phenylcarbamoyloxy]-tetrahydro-pyran-2-carboxylic acid allyl ester(922173-25-9)
• EPA Substance Registry System: (2S,3S,4S,5R,6S)-3,4,5-Tris-allyloxycarbonyloxy-6-[4-(tert-butyl-dimethyl-silanyloxymethyl)-phenylcarbamoyloxy]-tetrahydro-pyran-2-carboxylic acid allyl ester(922173-25-9)

Safety Data

• Hazardous Substances Data: 922173-25-9(Hazardous Substances Data)

Upstream product

• 135605-97-9 tert-butyldimethyl-4-nitrobenzyloxysilane 
• 131230-76-7 4-[(tert-butyldimethylsilyloxy)methyl]aniline 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 619-73-8 4-nitrobenzyl chloride 
• 922173-16-8 allyl 1,2,3,4-tetra-O-(allyloxycarbonyl)-D-glucopyranosiduronate 
• 922173-23-7 tert-butyl[(4-isocyanatophenyl)methoxy]dimethylsilane 

Downstream Products

• 922173-41-9 (2S,3S,4S,5R,6S)-3,4,5-Tris-allyloxycarbonyloxy-6-[4-({methyl-[2-(4-nitro-phenoxycarbonyloxy)-ethyl]-carbamoyloxy}-methyl)-phenylcarbamoyloxy]-tetrahydro-pyran-2-carboxylic acid allyl ester 
• 922173-31-7 (2S,3S,4S,5R,6S)-3,4,5-Tris-allyloxycarbonyloxy-6-[4-(4-nitro-phenoxycarbonyloxymethyl)-phenylcarbamoyloxy]-tetrahydro-pyran-2-carboxylic acid allyl ester 
• 922173-39-5 (2S,3S,4S,5R,6S)-3,4,5-Tris-allyloxycarbonyloxy-6-(4-{[(2-hydroxy-ethyl)-methyl-carbamoyloxy]-methyl}-phenylcarbamoyloxy)-tetrahydro-pyran-2-carboxylic acid allyl ester 
• 922173-27-1 (2S,3S,4S,5R,6S)-3,4,5-Tris-allyloxycarbonyloxy-6-(4-hydroxymethyl-phenylcarbamoyloxy)-tetrahydro-pyran-2-carboxylic acid allyl ester 

Relevant articles and documents

Protecting groups for glucuronic acid: Application to the synthesis of new paclitaxel (taxol) derivatives

To prepare two new glucuronide conjugates, allyl ester and allyl carbonates were used as protecting groups of the glucuronic moiety. In this way, an aniline glycosyl carbamate spacer linked to the 2′-OH of paclitaxel was obtained. By using palladium chemistry, an efficient one-step removal of all the allyl groups at the end of the synthesis afforded the desired compounds in good yields.