924708-81-6

Basic information

• Product Name: 1H-Pyrrole-1,2-dicarboxylic acid, 5-bromo-, 1-(1,1-dimethylethyl) 2-methyl ester
• Synonyms: 1H-Pyrrole-1,2-dicarboxylic acid, 5-bromo-, 1-(1,1-dimethylethyl) 2-methyl ester;1-tert-Butyl 2-methyl 5-bromo-1H-pyrrole-1,2-dicarboxylate
• CAS NO: 924708-81-6
• Molecular Formula: C11H14BrNO4
• Molecular Weight: 304.14
• Product Categories: API intermediates
• Mol File: 924708-81-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-Pyrrole-1,2-dicarboxylic acid, 5-bromo-, 1-(1,1-dimethylethyl) 2-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-1,2-dicarboxylic acid, 5-bromo-, 1-(1,1-dimethylethyl) 2-methyl ester(924708-81-6)
• EPA Substance Registry System: 1H-Pyrrole-1,2-dicarboxylic acid, 5-bromo-, 1-(1,1-dimethylethyl) 2-methyl ester(924708-81-6)

Safety Data

• Hazardous Substances Data: 924708-81-6(Hazardous Substances Data)

Usage

General Description

1H-Pyrrole-1,2-dicarboxylic acid, 5-bromo-, 1-(1,1-dimethylethyl) 2-methyl ester is a chemical compound that is used in the pharmaceutical industry. It is a derivative of pyrrole and is commonly used in the synthesis of various pharmaceutical drugs. 1H-Pyrrole-1,2-dicarboxylic acid, 5-bromo-, 1-(1,1-dimethylethyl) 2-methyl ester is known for its potential therapeutic properties and is being researched for its potential use in the treatment of various medical conditions. In addition, it is also used as a building block in organic synthesis and can be modified to create a wide range of chemical compounds. Overall, 1H-Pyrrole-1,2-dicarboxylic acid, 5-bromo-, 1-(1,1-dimethylethyl) 2-methyl ester is a versatile and important compound in the field of pharmaceuticals and organic chemistry.

Upstream product

• 117657-38-2 2,5-dibromopyrrole-1-carboxylic acid tert-butyl ester 
• 79-22-1 methyl chloroformate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 934-07-6 5-bromo-1H-pyrrole-2-carboxylic acid methyl ester 

Downstream Products

• 1519002-13-1 methyl 5-(4-isopropoxy-3-methoxyphenyl)-1H-pyrrole-2-carboxylate 
• 1578238-22-8 C₂₁H₂₇NO₆ 

Relevant articles and documents

Nickel-Catalyzed Decarboxylative Cross-Coupling of Bicyclo[1.1.1]pentyl Radicals Enabled by Electron Donor-Acceptor Complex Photoactivation

The use of bicyclo[1.1.1]pentanes (BCPs) as para-disubstituted aryl bioisosteres has gained considerable momentum in drug development programs. Carbon-carbon bond formation via transition-metal-mediated cross-coupling represents an attractive strategy to generate BCP-aryl compounds for late-stage functionalization, but these typically require reactive organometallics to prepare BCP nucleophiles on demand from [1.1.1]propellane. In this study, the synthesis and Ni-catalyzed functionalization of BCP redox-active esters with (hetero)aryl bromides via the action of a photoactive electron donor-acceptor complex are reported.