926658-81-3

Basic information

• Product Name: 9-Azabicyclo[3.3.1]nonan-3-one, 9-[(4-chlorophenyl)sulfonyl]-
• CAS NO: 926658-81-3
• Molecular Formula: C14H16ClNO3S
• Molecular Weight: 313.805
• Mol File: 926658-81-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 9-Azabicyclo[3.3.1]nonan-3-one, 9-[(4-chlorophenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 9-Azabicyclo[3.3.1]nonan-3-one, 9-[(4-chlorophenyl)sulfonyl]-(926658-81-3)
• EPA Substance Registry System: 9-Azabicyclo[3.3.1]nonan-3-one, 9-[(4-chlorophenyl)sulfonyl]-(926658-81-3)

Safety Data

• Hazardous Substances Data: 926658-81-3(Hazardous Substances Data)

Upstream product

• 72761-60-5 9-azabicyclo<3.3.1>nonan-3-one hydrochloride 
• 98-60-2 4-chlorobenzenesulfonyl chloride 

Downstream Products

• 926659-03-2 9-(4-chlorophenylsulfonyl)-2-(hydroxymethylene)-9-azabicyclo[3.3.1]nonan-3-one 
• 1227476-05-2 C₁₅H₁₆ClNO₄S 
• 1227476-08-5 C₁₆H₁₅ClF₃NO₄S 
• 1227476-09-6 C₁₆H₁₆ClF₂NO₄S 
• 926659-13-4 C₁₇H₂₀ClNO₃S₃ 

Relevant articles and documents

BRIDGED N-CYCLIC SULFONAMIDO INHIBITORS OF GAMMA SECRETASE

The invention provides N-cyclic sulfonamido compounds and salts of Formula (I): wherein A is as described in the specification and R1 and R2combine to form a [3.3.1] or a [3.2.1] ring system, where the nitrogen is attached to the two bridgehead carbons, and the [3.3.1] or [3.2.1] ring systems are optionally fused with an heteroaryl or heterocycloalkyl ring. Compounds of Formula (I) are useful in treating or preventing cognitive disorders, such as Alzheimer's Disease. The invention also encompasses pharmaceutical compositions comprising compounds of Formula I, methods of treating cognitive disorders, such as Alzheimer's disease, and the intermediates useful in preparing the compounds of Formula (I).