927177-00-2

Basic information

• Product Name: 5-Pyrimidinecarboxamide, 2-chloro-4-(cyclohexylamino)-N-(2-phenylethyl)-
• CAS NO: 927177-00-2
• Molecular Formula: C19H23ClN4O
• Molecular Weight: 358.871
• Mol File: 927177-00-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Pyrimidinecarboxamide, 2-chloro-4-(cyclohexylamino)-N-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarboxamide, 2-chloro-4-(cyclohexylamino)-N-(2-phenylethyl)-(927177-00-2)
• EPA Substance Registry System: 5-Pyrimidinecarboxamide, 2-chloro-4-(cyclohexylamino)-N-(2-phenylethyl)-(927177-00-2)

Safety Data

• Hazardous Substances Data: 927177-00-2(Hazardous Substances Data)

Upstream product

• 2972-52-3 2,4-dichloropyrimidine-5-carbonyl chloride 
• 23945-44-0 2,4-dihydroxypyrimidine-5-carboxylic acid 
• 64-04-0 phenethylamine 
• 927176-99-6 2,4-dichloro-pyrimidine-5-carboxylic acid phenethylamide 
• 108-91-8 cyclohexylamine 

Relevant articles and documents

2-Cyano-pyrimidines: A new chemotype for inhibitors of the cysteine protease cathepsin K

Starting from the purine lead structure 1, a new series of cathepsin K inhibitors based on a pyrimidine scaffold have been explored. Investigations of P3 and P2 substituents based on molecular modeling suggestions resulted in potent cathepsin K inhibitors