928651-91-6

Basic information

• Product Name: 2-tert-butoxycarbonylamino-3-phenyl-thiopropionic acid S-(2-{[2-(6-amino-purin-9-yl)-ethoxymethyl]-[2-(2-tert-butoxycarbonylamino-3-phenyl-propionylsulfanyl)-ethoxy]-phosphinoyloxy}-ethyl) ester
• CAS NO: 928651-91-6
• Molecular Weight: 888.015
• Mol File: 928651-91-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-tert-butoxycarbonylamino-3-phenyl-thiopropionic acid S-(2-{[2-(6-amino-purin-9-yl)-ethoxymethyl]-[2-(2-tert-butoxycarbonylamino-3-phenyl-propionylsulfanyl)-ethoxy]-phosphinoyloxy}-ethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tert-butoxycarbonylamino-3-phenyl-thiopropionic acid S-(2-{[2-(6-amino-purin-9-yl)-ethoxymethyl]-[2-(2-tert-butoxycarbonylamino-3-phenyl-propionylsulfanyl)-ethoxy]-phosphinoyloxy}-ethyl) ester(928651-91-6)
• EPA Substance Registry System: 2-tert-butoxycarbonylamino-3-phenyl-thiopropionic acid S-(2-{[2-(6-amino-purin-9-yl)-ethoxymethyl]-[2-(2-tert-butoxycarbonylamino-3-phenyl-propionylsulfanyl)-ethoxy]-phosphinoyloxy}-ethyl) ester(928651-91-6)

Safety Data

• Hazardous Substances Data: 928651-91-6(Hazardous Substances Data)

Upstream product

• 81000-39-7 (S)-2-((tert-butoxycarbonyl)amino)-3-phenylpropanethioic S-acid 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 928652-07-7 2-tert-butoxycarbonylamino-3-phenyl-thiopropionic acid S-(2-bromo-ethyl) ester 
• 106941-25-7 Adefovir 

Relevant articles and documents

Design and synthesis of novel bis(l-amino acid) ester prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA) with improved anti-HBV activity

A series of novel bis(l-amino acid) ester prodrugs of 9-[2-(phosphonomethoxy)ethyl] adenine (PMEA) was synthesized and their anti-HBV activity was evaluated in HepG 2 2.2.15 cells. Compounds 11, 12, 21, 22, 26, and 27 demonstrated more potent anti-HBV act